
DK: Jeg har en stor interesse i stråleterapi i gynækologisk kræft. Jeg er formand for GEC ESTRO gyn arbejdsgruppen og er også i koordinator gruppen i EMBRACE studiet (embracestudy.dk). Jeg er især engageret i at udvikle en forbedret forståelse af udviklingen af toksicitet og sygdomsudfald og derudover engageret i forståelsen af relationen mellem klinisk udfald og patient/behandlings karakteristika. Samtidig er jeg interesseret i brachyterapi teknologi. Jeg koordinerer internationale indsatser for at facilitere og promovere in vivo dosimetri gennem netværksmøder, fælles forskningsaktiviteter og samarbejder med industri for at understøtte at forbedret teknologi kan blive tilgængelig for patienter.
UK: I have a major interest in gynaecological cancer radiotherapy. I am chairing the GEC ESTRO gyn working group, and I am in the EMBRACE study coordinator group (www.embracestudy.dk). I am particularly engaged in developing improved understanding development of toxicity and disease outcome and to understand the relation between clinical outcome and patient/treatment characteristics. Furthermore, I am interested in brachytherapy technology. I am coordinating international efforts to facilitate and promote in vivo dosimetry through network meetings, joint research activities, and collaboration with industry to support that improved technology can become available for patients.
Arbejdsgrupper Publikationer- Bowel morbidity following radiochemotherapy and image-guided adaptive brachytherapy for cervical cancer: Physician- and patient reported outcome from the EMBRACE study. Radiother Oncol. 2018 Jun; 127(3): 431-439 2018
- Dwell time verification in brachytherapy based on time resolved in vivo dosimetry. Phys Med. 2019 Apr;60:156-161. 2019
- Assessment of dose to functional sub-structures in the lower urinary tract in locally advanced cervical cancer radiotherapy. Phys Med. 2019 Mar;59:127-132. 2019
- Risk Factors for Ureteral Stricture After Radiochemotherapy Including Image Guided Adaptive Brachytherapy in Cervical Cancer: Results From the EMBRACE Studies. Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):887-894. 2019
- Isodose surface volumes in cervix cancer brachytherapy: Change of practice from standard (Point A) to individualized image guided adaptive (EMBRACE I) brachytherapy. Radiother Oncol. 129 (3), pp. 567-574 2018
- Fatigue, insomnia and hot flashes after definitive radiochemotherapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: An analysis from the EMBRACE study. Radiother Oncol. 127(3): pp. 440-448 2018
- The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clinical and translational Radiation Oncology. 9: 48-60 2018
- Physician assessed and patient reported lower limb edema after definitive radio(chemo)therapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study. Radiother Oncol. 127(3), pp. 449-455 2018
- Physician assessed and patient reported urinary morbidity after radio-chemotherapy and image guided adaptive brachytherapy for locally advanced cervical cancer. Radiother Oncol. 127(3): 423-430 2018
- Time-resolved in vivo dosimetry for source tracking in brachytherapy. Brachytherapy. 2018 Jan - Feb; 17(1): 122-132 2018
- Reporting of Late Morbidity After Radiation Therapy in Large Prospective Studies: A Descriptive Review of the Current Status. Int J Radiat Oncol Biol Phys. 2019 Aug 27. 2019
- Image-guided Adaptive Brachytherapy for Cervix Cancer - A Story of Successful Collaboration within the GEC-ESTRO GYN Network and the EMBRACE Studies. Clin Oncol (R Coll Radiol). 2018 Jul;30(7):397-399. 2018
- Treatment delivery verification in brachytherapy: Prospects of technology innovation. Brachytherapy. 2018 Jan - Feb;17(1):1-6. 2018
- Importance of Technique, Target Selection, Contouring, Dose Prescription, and Dose-Planning in External Beam Radiation Therapy for Cervical Cancer: Evolution of Practice From EMBRACE-I to II. Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):885-894. 2019
- Late, persistent, substantial, treatment-related symptoms after radiotherapy (LAPERS): A new method for longitudinal analysis of late morbidity - applied in the EMBRACE study. Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):300-309. 2019
- Image registration, contour propagation and dose accumulation of external beam and brachytherapy in gynecological radiotherapy. Radiother Oncol. 2020 Feb;143:1-11. 2019
- Importance of training in external beam treatment planning for locally advanced cervix cancer: Report from the EMBRACE II dummy run. Radiother Oncol. 2019 Apr;133:149-155. 2019
- Evaluation of a new prognostic tumor score in locally advanced cervical cancer integrating clinical examination and magnetic resonance imaging. nt J Radiat Oncol Biol Phys. 2020 Mar 15;106(4):754-763. 2019
- Ring Versus Ovoids and Intracavitary Versus Intracavitary-Interstitial Applicators in Cervical Cancer Brachytherapy: Results From the EMBRACE I Study. Int J Radiat Oncol Biol Phys. 2020 Apr 1;106(5):1052-1062. 2020
- MRI-based contouring of functional sub-structures of the lower urinary tract in gynaecological radiotherapy. Radiother Oncol. 2020 Apr;145:117-124. 2020
- Persistence of late substantial patient-reported symptoms (LAPERS) after radiochemotherapy including image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study. Int J Radiat Oncol Biol Phys. 2020 Aug 24;S0360-3016(20)34139-0. 2020
- 3D source tracking and error detection in HDR using two independent scintillator dosimetry systems Med Phys . 2020 Nov 22. 2020
- Future directions of in vivo dosimetry for external beam radiotherapy and brachytherapy EDITORIAL| VOLUME 16, P18-19, OCTOBER 01, 2020 2020
- In vivo dosimetry in brachytherapy: Requirements and future directions for research, development, and clinical practice REVIEW ARTICLE| VOLUME 16, P1-11, OCTOBER 01, 2020 2020
- Dose-Volume Effects and Risk Factors for Late Diarrhea in Cervix Cancer Patients after Radiochemotherapy with Image-Guided Adaptive Brachytherapy in the EMBRACE I Study. Int J Radiat Oncol Biol Phys. 2020 Oct 14:S0360-3016(20)34393-5. 2020
- Importance of the ICRU bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: An EMBRACE analysis. Radiother Oncol. 2020 Oct 14:S0167-8140(20)30839-2. 2020
- Persistence of Late Substantial Patient-Reported Symptoms (LAPERS) After Radiochemotherapy Including Image Guided Adaptive Brachytherapy for Locally Advanced Cervical Cancer: A Report From the EMBRACE Study. Int J Radiat Oncol Biol Phys. 2020 Aug 25:S0360-3016(20)34139-0. 2020
- Evidence-Based Dose Planning Aims and Dose Prescription in Image-Guided Brachytherapy Combined With Radiochemotherapy in Locally Advanced Cervical Cancer. Semin Radiat Oncol. 2020 Oct;30(4):311-327. 2020
- Dose planning variations related to delineation variations in MRI-guided brachytherapy for locally advanced cervical cancer Brachytherapy . Mar-Apr 2020;19(2):146-153. 2020
- A Cost-Utility Analysis of Magnetic Resonance (MR) Guided Brachytherapy Versus Two-Dimensional and Computed Tomography (CT) Guided Brachytherapy for Locally Advanced Cervical Cancer Int J Radiat Oncol Biol Phys . 2020 Jul 1;107(3):512-521. 2020
- Implementing an online radiotherapy quality assurance programme with supporting continuous medical education - report from the EMBRACE-II evaluation of cervix cancer IMRT contouring Radiother Oncol . 2020 Jun;147:22-29. 2020
- Image guidance in radiation therapy for better cure of cancer Mol Oncol . 2020 Jul;14(7):1470-1491. 2020
- Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study Gynecol Oncol . 2020 Oct;159(1):136-141. 2020
- Education and training for image-guided adaptive brachytherapy for cervix cancer-The (GEC)-ESTRO/EMBRACE perspective Brachytherapy . Nov-Dec 2020;19(6):827-836. 2020
- Phantom-based quality assurance for multicenter quantitative MRI in locally advanced cervical cancer adiother Oncol . 2020 Sep 12;S0167-8140(20)30785-4. 2020
- Initiatives for education, training, and dissemination of morbidity assessment and reporting in a multiinstitutional international context: Insights from the EMBRACE studies on cervical cancer Brachytherapy . Nov-Dec 2020;19(6):837-849. 2020
- Management of oligo-metastatic and oligo-recurrent cervical cancer: A pattern of care survey within the EMBRACE research network Radiother Oncol . 2020 Nov 2;155:151-159. 2020
- DOSIMETRIC IMPACT OF INTRA-FRACTION MOTION IN ONLINE-ADAPTIVE IMPT FOR CERVICAL CANCER Int J Radiat Oncol Biol Phys . 2020 Nov 20;S0360-3016(20)34559-4. 2020
- In vivo dosimetry in brachytherapy: Requirements and future directions for research, development, and clinical practice Physics and Imaging in Radiation Oncology, 2020, 16, pp. 1-11 2020
- Future directions of in vivo dosimetry for external beam radiotherapy and brachytherapy Physics and Imaging in Radiation Oncology, 2020, 16, pp. 18-19 2020
- Risk factors and dose-effects for bladder fistula, bleeding and cystitis after radiotherapy with imaged-guided adaptive brachytherapy for cervical cancer: an EMBRACE analysis Radiother Oncol. 2021 Feb 2 2021