Kari Tanderup

Professor Kræftafdelingen/DCPT, Aarhus University Hospital karitand@rm.dk
Forskningsområde

DK: Jeg har en stor interesse i stråleterapi i gynækologisk kræft. Jeg er formand for GEC ESTRO gyn arbejdsgruppen og er også i koordinator gruppen i EMBRACE studiet (embracestudy.dk). Jeg er især engageret i at udvikle en forbedret forståelse af udviklingen af toksicitet og sygdomsudfald og derudover engageret i forståelsen af relationen mellem klinisk udfald og patient/behandlings karakteristika. Samtidig er jeg interesseret i brachyterapi teknologi. Jeg koordinerer internationale indsatser for at facilitere og promovere in vivo dosimetri gennem netværksmøder, fælles forskningsaktiviteter og samarbejder med industri for at understøtte at forbedret teknologi kan blive tilgængelig for patienter. 

UK: I have a major interest in gynaecological cancer radiotherapy. I am chairing the GEC ESTRO gyn working group, and I am in the EMBRACE study coordinator group (www.embracestudy.dk). I am particularly engaged in developing improved understanding development of toxicity and disease outcome and to understand the relation between clinical outcome and patient/treatment characteristics. Furthermore, I am interested in brachytherapy technology. I am coordinating international efforts to facilitate and promote in vivo dosimetry through network meetings, joint research activities, and collaboration with industry to support that improved technology can become available for patients.

 Arbejdsgrupper Publikationer
  • Jensen NBK, Pötter R, Kirchheiner K, Fokdal L, Lindegaard JC, Kirisits C, Mazeron R, Mahantshetty U, Jürgenliemk-Schulz IM, Segedin B, Hoskin P, Tanderup K; EMBRACE Collaborative Group. Bowel morbidity following radiochemotherapy and image-guided adaptive brachytherapy for cervical cancer: Physician- and patient reported outcome from the EMBRACE study. Radiother Oncol. 2018 Jun; 127(3): 431-439 2018
  • Johansen JG, Kertzscher G, Jørgensen EB, Rylander S, Bentzen L, Hokland SB, Søndergaard CS, With AKM, Buus S, Tanderup K. Dwell time verification in brachytherapy based on time resolved in vivo dosimetry. Phys Med. 2019 Apr;60:156-161. 2019
  • Spampinato S, Fokdal L, Marinovskij E, Axelsen S, Pedersen EM, Pötter R, Lindegaard JC, Tanderup K. Assessment of dose to functional sub-structures in the lower urinary tract in locally advanced cervical cancer radiotherapy. Phys Med. 2019 Mar;59:127-132. 2019
  • Fokdal L, Tanderup K, Pötter R, Sturdza A, Kirchheiner K, Chargari C, Jürgenliemk-Schulz IM, Segedin B, Tan LT, Hoskin P, Mahantshetty U, Bruheim K, Rai B, Kirisits C, Lindegaard JC; EMBRACE Collaborative Group. Risk Factors for Ureteral Stricture After Radiochemotherapy Including Image Guided Adaptive Brachytherapy in Cervical Cancer: Results From the EMBRACE Studies. Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):887-894. 2019
  • Serban M, Kirisits C, Pötter R, de Leeuw A, Nkiwane K, Dumas I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Oinam A, Bownes P, Oosterveld B, De Brabandere M, Koedooder K, Marthinsen ABL, Lindegaard J, Tanderup K; EMBRACE Collaborative Group Isodose surface volumes in cervix cancer brachytherapy: Change of practice from standard (Point A) to individualized image guided adaptive (EMBRACE I) brachytherapy. Radiother Oncol. 129 (3), pp. 567-574 2018
  • Smet S, Pötter R, Haie-Meder C, Lindegaard JC, Schulz-Juergenliemk I, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van Limbergen E, Tanderup K, Kirchheiner K; EMBRACE Collaborative Group. Fatigue, insomnia and hot flashes after definitive radiochemotherapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: An analysis from the EMBRACE study. Radiother Oncol. 127(3): pp. 440-448 2018
  • Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, Tan LT, Haie-Meder C, Mahantshetty U, Segedin B, Hoskin P, Bruheim K, Rai B, Huang F, Van Limbergen E, Schmid M, Nesvacil N, Sturdza A, Fokdal L, Jensen NBK, Georg D, Assenholt M, Seppenwoolde Y, Nomden C, Fortin I, Chopra S, van der Heide U, Rumpold T, Lindegaard JC, Jürgenliemk-Schulz I; EMBRACE Collaborative Group. The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clinical and translational Radiation Oncology. 9: 48-60 2018
  • Najjari Jamal D, Pötter R, Haie-Meder C, Lindegaard JC, Juergenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Wiebe E, Cooper R, Tanderup K, Kirchheiner K; EMBRACE collaborative group. Physician assessed and patient reported lower limb edema after definitive radio(chemo)therapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study. Radiother Oncol. 127(3), pp. 449-455 2018
  • Fokdal L, Pötter R, Kirchheiner K, Lindegaard JC, Jensen NBK, Kirisits C, Chargari C, Mahantshetty U, Jürgenliemk-Schulz IM, Segedin B, Hoskin P, Tanderup K. Physician assessed and patient reported urinary morbidity after radio-chemotherapy and image guided adaptive brachytherapy for locally advanced cervical cancer. Radiother Oncol. 127(3): 423-430 2018
  • Johansen JG, Rylander S, Buus S, Bentzen L, Hokland SB, Søndergaard CS, With AKM, Kertzscher G, Tanderup K. Time-resolved in vivo dosimetry for source tracking in brachytherapy. Brachytherapy. 2018 Jan - Feb; 17(1): 122-132 2018
  • Vittrup AS, Kirchheiner K, Fokdal LU, Bentzen SM, Nout RA, Pötter R, Tanderup K Reporting of Late Morbidity After Radiation Therapy in Large Prospective Studies: A Descriptive Review of the Current Status. Int J Radiat Oncol Biol Phys. 2019 Aug 27. 2019
  • Tan LT, Tanderup K, Hoskin P, Cooper, Pötter R Image-guided Adaptive Brachytherapy for Cervix Cancer - A Story of Successful Collaboration within the GEC-ESTRO GYN Network and the EMBRACE Studies. Clin Oncol (R Coll Radiol). 2018 Jul;30(7):397-399. 2018
  • Tanderup K, Kirisits C, Damato AL Treatment delivery verification in brachytherapy: Prospects of technology innovation. Brachytherapy. 2018 Jan - Feb;17(1):1-6. 2018
  • Berger T, Seppenwoolde Y, Pötter R, Assenholt MS, Lindegaard JC, Nout RA, de Leeuw A, Jürgenliemk-Schulz I, Tan LT, Georg D, Kirisits C, Dumas I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Fokdal L, Tanderup K; EMBRACE Collaborative Group. Importance of Technique, Target Selection, Contouring, Dose Prescription, and Dose-Planning in External Beam Radiation Therapy for Cervical Cancer: Evolution of Practice From EMBRACE-I to II. Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):885-894. 2019
  • Kirchheiner K, Pötter R, Nout RA, Schwartz-Vittrup A, Holzner B, Bentzen SM, Tanderup K Late, persistent, substantial, treatment-related symptoms after radiotherapy (LAPERS): A new method for longitudinal analysis of late morbidity - applied in the EMBRACE study. Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):300-309. 2019
  • Swamidas J, Kirisits C, De Brabandere M, Hellebust TP, Siebert FA, Tanderup K. Image registration, contour propagation and dose accumulation of external beam and brachytherapy in gynecological radiotherapy. Radiother Oncol. 2020 Feb;143:1-11. 2019
  • Seppenwoolde Y, Assenholt MS, Georg D, Nout R, Tan LT, Rumpold T, de Leeuw A, Jürgenliemk-Schulz I, Kirisits C, Pötter R, Lindegaard JC, Tanderup K; EMBRACE Collaborative Group. Importance of training in external beam treatment planning for locally advanced cervix cancer: Report from the EMBRACE II dummy run. Radiother Oncol. 2019 Apr;133:149-155. 2019
  • Lindegaard JC, Petric P, Lindegaard AM, Tanderup K, Fokdal LU. Evaluation of a new prognostic tumor score in locally advanced cervical cancer integrating clinical examination and magnetic resonance imaging. nt J Radiat Oncol Biol Phys. 2020 Mar 15;106(4):754-763. 2019
  • Serban M, Kirisits C, de Leeuw A, Pötter R, Jürgenliemk-Schulz I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Oinam A, Bownes P, Oosterveld B, De Brabandere M, Koedooder K, Langeland Marthinsen AB, Whitney D, Lindegaard J, Tanderup K; EMBRACE Collaborative Group. Ring Versus Ovoids and Intracavitary Versus Intracavitary-Interstitial Applicators in Cervical Cancer Brachytherapy: Results From the EMBRACE I Study. Int J Radiat Oncol Biol Phys. 2020 Apr 1;106(5):1052-1062. 2020
  • Spampinato S, Tanderup K, Marinovskij E, Axelsen S, Pedersen EM, Pötter R, Lindegaard JC, Fokdal L. MRI-based contouring of functional sub-structures of the lower urinary tract in gynaecological radiotherapy. Radiother Oncol. 2020 Apr;145:117-124. 2020
  • Vittrup AS, Tanderup K, Bentzen SM, Jensen NBK, Spampinato S, Fokdal LU, Lindegaard JC, Sturdza A, Schmid M, Segedin B, Jürgenliemk-Schulz IM, Bruheim K, Mahantshetty U, Haie-Meder C, Rai B, Cooper R, van der Steen-Banasik E, Sundset M, Huang F, Nout RA, Villafranca E, Van Limbergen E, Pieters BR, Tan LT, Lutgens LCHW, Hoskin P, Pötter R, Kirchheiner K; EMBRACE Collaborative Group. Persistence of late substantial patient-reported symptoms (LAPERS) after radiochemotherapy including image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study. Int J Radiat Oncol Biol Phys. 2020 Aug 24;S0360-3016(20)34139-0. 2020
  • Haydee M Linares Rosales, Jacob G Johansen, Gustavo Kertzscher, Kari Tanderup, Luc Beaulieu, Sam Beddar 3D source tracking and error detection in HDR using two independent scintillator dosimetry systems Med Phys . 2020 Nov 22. 2020
  • Frank Verhaegen, Gabriel P. Fonseca, Jacob G. Johansen, Luc Beaulieu, Sam Beddar, Peter Greer, Nuria Jornet, Gustavo Kertzscher, Boyd McCurdy, Ryan L. Smith, Ben Mijnheer, Igor Olaciregui-Ruiz, Kari Tanderup Future directions of in vivo dosimetry for external beam radiotherapy and brachytherapy EDITORIAL| VOLUME 16, P18-19, OCTOBER 01, 2020 2020
  • Gabriel P. Fonseca, Jacob G. Johansen, Ryan L. Smith, Luc Beaulieu, Sam Beddar, Gustavo Kertzscher, Frank Verhaegen, Kari Tanderup In vivo dosimetry in brachytherapy: Requirements and future directions for research, development, and clinical practice REVIEW ARTICLE| VOLUME 16, P1-11, OCTOBER 01, 2020 2020
  • Kibsgaard Jensen NB, Pötter R, Spampinato S, Fokdal LU, Chargari C, Lindegaard JC, Schmid M, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Wiebe E, Cooper R, Van der Steen-Banasik E, Van Limbergen E, Sundset M, Pieters BR, Nout R, Kirisits , Kirchheiner K, Tanderup K; EMBRACE Collaborative Group. Dose-Volume Effects and Risk Factors for Late Diarrhea in Cervix Cancer Patients after Radiochemotherapy with Image-Guided Adaptive Brachytherapy in the EMBRACE I Study. Int J Radiat Oncol Biol Phys. 2020 Oct 14:S0360-3016(20)34393-5. 2020
  • Spampinato S, Fokdal LU, Pötter R, Haie-Meder C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van der Steen-Banasik E, Van Limbergen E, Sundset M, Westerveld H, Nout RA, Jensen NBK, Kirisits C, Kirchheiner K, Tanderup K; EMBRACE Collaborative Group. Importance of the ICRU bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: An EMBRACE analysis. Radiother Oncol. 2020 Oct 14:S0167-8140(20)30839-2. 2020
  • Vittrup AS, Tanderup K, Bentzen SM, Jensen NBK, Spampinato S, Fokdal LU, Lindegaard JC, Sturdza A, Schmid M, Segedin B, Jürgenliemk-Schulz IM, Bruheim K, Mahantshetty U, Haie-Meder C, Rai B, Cooper R, van der Steen-Banasik E, Sundset M, Huang F, Nout RA, Villafranca E, Van Limbergen E, Pieters BR, Tan LT, Lutgens LCHW, Hoskin P, Pötter R, Kirchheiner K; EMBRACE Collaborative Group. Persistence of Late Substantial Patient-Reported Symptoms (LAPERS) After Radiochemotherapy Including Image Guided Adaptive Brachytherapy for Locally Advanced Cervical Cancer: A Report From the EMBRACE Study. Int J Radiat Oncol Biol Phys. 2020 Aug 25:S0360-3016(20)34139-0. 2020
  • Tanderup K, Nesvacil N, Kirchheiner K, Serban M, Spampinato S, Jensen NBK, Schmid M, Smet S, Westerveld H, Ecker S, Mahantshetty U, Swamidas J, Chopra S, Nout R, Tan LT, Fokdal L, Sturdza A, Jürgenliemk-Schulz I, de Leeuw A, Lindegaard JC, Kirisits C, Pötter R Evidence-Based Dose Planning Aims and Dose Prescription in Image-Guided Brachytherapy Combined With Radiochemotherapy in Locally Advanced Cervical Cancer. Semin Radiat Oncol. 2020 Oct;30(4):311-327. 2020
  • Lauren Bell, Lois Holloway, Kjersti Bruheim, Primož Petrič, Christian Kirisits, Kari Tanderup, Richard Pötter, Shalini Vinod, Karen Lim, Elise Pogson, Peter Metcalfe, Taran Paulsen Hellebust Dose planning variations related to delineation variations in MRI-guided brachytherapy for locally advanced cervical cancer Brachytherapy . Mar-Apr 2020;19(2):146-153. 2020
  • Johnna Perdrizet, David D'Souza, Julia Skliarenko, Michelle Ang, Lisa Barbera, Eric Gutierrez, Ananth Ravi, Kari Tanderup, Padraig Warde, Kelvin Chan, Wanrudee Isaranuwatchai, Michael Milosevic A Cost-Utility Analysis of Magnetic Resonance (MR) Guided Brachytherapy Versus Two-Dimensional and Computed Tomography (CT) Guided Brachytherapy for Locally Advanced Cervical Cancer Int J Radiat Oncol Biol Phys . 2020 Jul 1;107(3):512-521. 2020
  • Simon L Duke, Li-Tee Tan, Nina B K Jensen, Tamara Rumpold, Astrid A C De Leeuw, Christian Kirisits, Jacob C Lindegaard, Kari Tanderup, Richard C Pötter, Remi A Nout, Ina M Jürgenliemk-Schulz Implementing an online radiotherapy quality assurance programme with supporting continuous medical education - report from the EMBRACE-II evaluation of cervix cancer IMRT contouring Radiother Oncol . 2020 Jun;147:22-29. 2020
  • Vincent Grégoire, Matthias Guckenberger, Karin Haustermans, Jan J W Lagendijk, Cynthia Ménard, Richard Pötter, Ben J Slotman, Kari Tanderup, Daniela Thorwarth, Marcel van Herk, Daniel Zips Image guidance in radiation therapy for better cure of cancer Mol Oncol . 2020 Jul;14(7):1470-1491. 2020
  • J Knoth, R Pötter, I M Jürgenliemk-Schulz, C Haie-Meder, L Fokdal, A Sturdza, P Hoskin, U Mahantshetty, B Segedin, K Bruheim, E Wiebe, B Rai, R Cooper, E van der Steen-Banasik , E van Limbergen , B R Pieters, M Sundset, L T Tan, R A Nout, K Tanderup, C Kirisits, N Nesvacil, J C Lindegaard, M P Schmid Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study Gynecol Oncol . 2020 Oct;159(1):136-141. 2020
  • Tan LT, Tanderup K, Kirisits C, Mahantshetty U, Swamidas J, Jürgenliemk-Schulz I, Lindegaard J, de Leeuw A, Nesvacil N, Assenholt M, Berger D, Diendorfer T, Dimopoulos J, Duke S, Ecker S, Fokdal L, Hellebust T, Jensen N, Kirchheiner K, Nout R, Petric P, Schmid M, Seppenwoolde Y, Sturdza A, Van Limbergen E, Haie-Meder C, Pötter R Education and training for image-guided adaptive brachytherapy for cervix cancer-The (GEC)-ESTRO/EMBRACE perspective Brachytherapy . Nov-Dec 2020;19(6):827-836. 2020
  • van Houdt PJ, Kallehauge JF, Tanderup K, Nout R, Zaletelj M, Tadic T, van Kesteren ZJ, van den Berg CAT, Georg D, Côté JC, Levesque IR, Swamidas J, Malinen E, Telliskivi S, Brynolfsson P, Mahmood F, van der Heide UA Phantom-based quality assurance for multicenter quantitative MRI in locally advanced cervical cancer adiother Oncol . 2020 Sep 12;S0167-8140(20)30785-4. 2020
  • Kirchheiner K, Smet S, Spampinato S, Jensen NBK, Vittrup AS, Fokdal L, Najjari-Jamal D, Westerveld HG, Lindegaard JC, Kirisits C, De Leeuw A, Schmid MP, Tan LT, Nout RA, Jürgenliemk-Schulz IM, Pötter R, Tanderup K Initiatives for education, training, and dissemination of morbidity assessment and reporting in a multiinstitutional international context: Insights from the EMBRACE studies on cervical cancer Brachytherapy . Nov-Dec 2020;19(6):837-849. 2020
  • Chopra S, Mangaj A, Sharma A, Tan LT, Sturdza A, Jürgenliemk-Schulz I, Han K, Huang F, Schmid MP, Fokdal L, Chargari C, Diendorfer T, Tanderup K, Potter R, Nout RA Management of oligo-metastatic and oligo-recurrent cervical cancer: A pattern of care survey within the EMBRACE research network Radiother Oncol . 2020 Nov 2;155:151-159. 2020
  • Berger T, Godart J, Jagt T, Vittrup AS, Fokdal LU, Lindegaard JC, Jensen NBK, Zolnay A, Reijtenbagh D, Trnkova P, Tanderup K, Hoogeman DOSIMETRIC IMPACT OF INTRA-FRACTION MOTION IN ONLINE-ADAPTIVE IMPT FOR CERVICAL CANCER Int J Radiat Oncol Biol Phys . 2020 Nov 20;S0360-3016(20)34559-4. 2020
  • Fonseca, G.P., Johansen, J.G., Smith, R.L. Beaulieu, L., Beddar, S., Kertzscher, G.,Verhaegen, F., Tanderup, K In vivo dosimetry in brachytherapy: Requirements and future directions for research, development, and clinical practice Physics and Imaging in Radiation Oncology, 2020, 16, pp. 1-11 2020
  • Verhaegen, F., Fonseca, G.P., Johansen, J.G., Beaulieu, L., Beddar, S., Greer, P., Jornet, N., Kertzscher, G., McCurdy, B., Smith, R.L., Mijnheer, B., Olaciregui-Ruiz, I., Tanderup, K. Future directions of in vivo dosimetry for external beam radiotherapy and brachytherapy Physics and Imaging in Radiation Oncology, 2020, 16, pp. 18-19 2020
  • Spampinato S, Fokdal LU, Pötter R, Haie-Meder C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van der Steen-Banasik E, Van Limbergen E, Sundset M, Westerveld H, Nout RA, Jensen NBK, Kirisits C, Kirchheiner K, Tanderup K; EMBRACE Collaborative Group. Risk factors and dose-effects for bladder fistula, bleeding and cystitis after radiotherapy with imaged-guided adaptive brachytherapy for cervical cancer: an EMBRACE analysis Radiother Oncol. 2021 Feb 2 2021