Morten Høyer

Ledende overlæge, professor Dansk Center for Partikelterapi, Aarhus University Hospital hoyer@aarhus.rm.dk
Forskningsområde

DK: Stereotaktisk strålebehandling af hjerne-, lunge- og levertumorer; radioterapi af hjernetumorer, prostata- og blærekræft, radioterapi af børn og unge og protonterapi; forskning i biologi, teknologi og kliniske aspekter inden for stereotaktisk strålebehandling, adaptive radioterapi; specielt fokus på udvikling af stråleskade, kliniske forsøg og protonterapi.

UK: Stereotactic radiotherapy of brain-, lung- and liver tumours; radiotherapy of brain tumours, prostate- and bladder cancer, radiotherapy of children and the young and proton therapy; research in biology, technology and clinical aspects within stereotactic radiotherapy, adaptive radiotherapy; especially focus on the development of radiation injury, clinical trials and proton therapy. 

Arbejdsgrupper Publikationer
  • Worm ES, Høyer M, Hansen R, Larsen LP, Weber B, Grau C, Poulsen PR. A Prospective Cohort Study of Gated Stereotactic Liver Radiation Therapy Using Continuous Internal Electromagnetic Motion Monitoring. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):366-375 2018
  • Bertholet J, Toftegaard J, Hansen R, Worm ES, Wan H, Parikh PJ, Weber B, Høyer M, Poulsen PR. Automatic online and real-time tumour motion monitoring during stereotactic liver treatments on a conventional linac by combined optical and sparse monoscopic imaging with kilovoltage x-rays (COSMIK). Phys Med Biol. 63(5); pp. 055012 2018
  • Thor M, Jackson A, Zelefsky MJ, Steineck G, Karlsdòttir A, Høyer M, Liu M, Nasser NJ, Petersen SE, Moiseenko V, Deasy JO Inter-institutional analysis demonstrates the importance of lower than previously anticipated dose regions to prevent late rectal bleeding following prostate radiotherapy. Radiother Oncol. 127(1), pp. 88-95 2018
  • Eekers DB, In 't Ven L, Roelofs E, Postma A, Alapetite C, Burnet NG, Calugaru V, Compter l, Coremans IEM, Høyer M, Lambrecht M, Nyström PW, Romero AM, Paulsen F, Perpar A, de Ruysscher D, Renard L, Timmermann B, Vitek P, Weber DC, van der Weide HL, Whitfield GA, Wiggenraad R, Troost EGC; “European Particle Therapy Network” of ESTRO. The EPTN consensus-based atlas for CT- and MR-based contouring in neuro-oncology. Radiother Oncol. 128(1), pp. 37-43 2018
  • Lambrecht M, Eekers DBP, Alapetite C, Burnet NG, Calugaru V, Coremans IEM, Fossati P, Høyer M, Langendijk JA, Romero AM, Paulsen F, Perpar A, Renard L, de Ruysscher D2 Timmermann B, Vitek P, Weber DC, van der Weide HL, Whitfield GA, Wiggenraad R, Roelofs E, Nyström PW, Troost EGC; work package 1 of the taskforce “European Particle Therapy Network” of ESTRO. Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus. Radiother Oncol. 128(1), pp. 26-36 2018
  • Nankali S, Worm ES, Hansen R, Weber B, Høyer M, Zirak A, Poulsen PR. Geometric and dosimetric comparison of four intrafraction motion adaptation strategies for stereotactic liver radiotherapy. Phys Med Biol. 2018 Jul 16;63(14) 2018
  • Schaub SK, Hartvigson PE, Lock MI, Høyer M, Brunner TB, Cardenes HR, Dawson LA, Kim EY, Mayr NA, Lo SS, Apisarnthanarax S. Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: Current Trends and Controversies. Technol Cancer Res Treat. 17:1533033818790217 2018
  • Colvill E, Petersen JBB, Hansen R, Worm E, Skouboe S, Høyer M, Poulsen PR. Validation of fast motion-including dose reconstruction for proton scanning therapy in the liver. Phys Med Biol. 63(22):225021 2018
  • Skouboe S, Ravkilde T, Bertholet J, Hansen R, Worm ES, Muurholm CG, Weber B, Høyer M, Poulsen PR. First clinical real-time motion-including tumor dose reconstruction during radiotherapy delivery. Radiother Oncol. 2019 Oct;139:66-71. 2019
  • Skouboe S, Poulsen PR, Muurholm CG, Worm E, Hansen R, Høyer M, Ravkilde T. Simulated real-time dose reconstruction for moving tumors in stereotactic liver radiotherapy. Med Phys. 2019 Aug 29. 2019
  • Mortensen HR, Høyer M, Grau C. Proton therapy Ugeskr Laeger. 2019 Oct 14;181(20A). 2019
  • Overgaard J, Muren LP, Høyer M, Grau C BIGART 2019 - adapting to the future. Acta Oncol. 2019 Oct;58(10):1323-1327. 2019
  • Toussaint L, Indelicato DJ, Stokkevåg CH, Lassen-Ramshad Y, Pedro C, Mikkelsen R, Di Pinto M, Li Z, Flampouri S, Vestergaard A, Petersen JBB, Schrøder H, Høyer M, Muren LP Radiation doses to brain substructures associated with cognition in radiotherapy of pediatric brain tumors. Acta Oncol. 2019 Oct;58(10):1457-1462. 2019
  • Haldbo-Classen L, Amidi A, Wu LM, Lukacova S, Oettingen GV, Gottrup H, Zachariae R, Høyer M Long-term cognitive dysfunction after radiation therapy for primary brain tumors. Acta Oncol. 2019 May;58(5):745-752. 2019
  • Fodor A, Lancia A, Ceci F, Picchio M, Hoyer M, Jereczek-Fossa BA, Ost P, Castellucci P, Incerti E, Di Muzio N, Ingrosso G. Oligorecurrent prostate cancer limited to lymph nodes: getting our ducks in a row : Nodal oligorecurrent prostate cancer. World J Urol. 2019 Dec;37(12):2607-2613 2018
  • Ervandian M, Djurhuus JC, Høyer M, Graugaard-Jensen C, Borre M. Long-term urodynamic findings following radical prostatectomy and salvage radiotherapy. Scand J Urol. 2018 Feb;52(1):20-26. 2017
  • Skouboe S, Poulsen PR, Muurholm CG, Worm E, Hansen R, Høyer M, Ravkilde T. Simulated real-time dose reconstruction for moving tumors in stereotactic liver radiotherapy. Med Phys. 2019 Nov;46(11):4738-4748. 2019
  • Toussaint L, Indelicato DJ, Muren LP, Li Z, Lassen-Ramshad Y, Kirby K, Pedro C, Mikkelsen R, Di Pinto M, Høyer M, Stokkevåg CH. Temporal lobe sparing radiotherapy with photons or protons for cognitive function preservation in paediatric craniopharyngioma. Radiother Oncol. 2019 Aug 28. pii: S0167-8140(19)33041-5. 2019
  • Widmark A, Gunnlaugsson A, Beckman L, Thellenberg-Karlsson C, Hoyer M, Lagerlund M, Kindblom J, Ginman C, Johansson B, Björnlinger K, Seke M, Agrup M, Fransson P, Tavelin B, Norman D, Zackrisson B, Anderson H, Kjellén E, Franzén L, Nilsson P. Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial. Lancet. 2019 Aug 3;394(10196):385-395. 2019
  • Dobrzycka M, Spychalski P, Rostkowska O, Wilczyński M, Kobiela P, Grąt M, Dell'Acqua V, Høyer M, Jereczek-Fossa BA. Stereotactic body radiation therapy for early-stage hepatocellular carcinoma - a systematic review on outcome. Acta Oncol. 2019 Dec;58(12):1706-1713. 2019
  • Spychalski P, Kobiela J, Antoszewska M, Błażyńska-Spychalska A, Jereczek-Fossa BA, Høyer M. Patient specific outcomes of charged particle therapy for hepatocellular carcinoma - A systematic review and quantitative analysis. Radiother Oncol. 2019 Mar;132:127-134. 2019
  • Hansen AT, Poulsen PR, Høyer M, Worm ES. Isotoxic dose prescription level strategies for stereotactic liver radiotherapy: the price of dose uniformity. Acta Oncol. 2019 Dec 13:1-7. 2019
  • Boysen AK, Spindler KL, Høyer M, Mortensen FV, Christensen TD, Farkas DK, Ording AG. Metastasis directed therapy for liver and lung metastases from colorectal cancer-A population-based study. Int J Cancer. 2018 Dec 15;143(12):3218-3226. 2018