PhD projects

DCCC Radiotherapy has supported PhD projects with funding and/or infrastructure. In December 2018, DCCC RT distributed partial funding for 18 PhD projects, and in 2021, 5 more projects received funding. Moreover, all affiliated radiotherapy PhD projects and fellows are included in our network. The list below includes PhD projects in the funding period of DCCC RT (i.e. until end of 2022).

List of PhD projects in DCCC RT:

  1. Dose-escalated radiotherapy for patients with hypoxic head and neck squamous cell carcinoma. Mette Saksø. Aarhus University Hospital. Project duration 2016-2021. PhD defence June 11 2021.
  2. Late urinary morbidity after radiotherapy in cervical cancer: Anatomy, dose and dose-effect. Sofia Spampinato. Aarhus University Hospital. Project duration 2017-2020. PhD defence September 4 2020.
  3. Data mining in head and neck cancer. Christian Rønn Hansen. Odense University Hospital/University of Southern Denmark. Project duration 2016-2022. PhD defence September 15 2022.
  4. Management of side effects in head and neck cancer by systematic use of PRO during radiotherapyCecilie Holländer-Mieritz. Rigshospitalet. PhD defence March 30 2023.
  5. Bowel morbidity after radiochemotherapy and image-guided adaptive brachytherapy in locally advanced cervical cancer within the EMBRACE study. Nina Boje Kibsgaard Jensen. Aarhus University Hospital. Project duration 2015-2020. PhD defence June 12 2020.
  6. Clinical potential of radiotherapy plan adaptation using an MR accelerator. Rasmus Lübeck Christiansen. Odense University Hospital/University of Southern Denmark. Project duration 2017-2021. PhD defence February 11 2022.
  7. Individualised risk estimation, proton therapy and breath-hold - Examples from breast cancer and liver metastasesLine Bjerregaard Stick. Rigshospitalet/University of Copenhagen. Project duration 2017-2020. 
  8. Multi-variable models of dose response for precision radiotherapy of advanced lung cancer. Christina Maria Lutz. Aarhus University Hospital. Project duration 2017-2020. PhD defence October 29 2020.
  9. Persistent late effect in cervix cancer patients after external radiotherapy with concomitant chemotherapy followed by brachytherapy. Anders Schwartz Vittrup. Aarhus University Hospital. Project duration 2018-2021. PhD defence September 10 2021.
  10. Risk of radiotherapy induced heart disease in patients treated for breast cancer. Marie Louise Milo. Aarhus University Hospital. Project duration 2018-2021. PhD defence October 29 2021.
  11. Advanced techniques to minimize side effects in young radiotherapy patients treated in the thoracic region. Laura Ann Rechner. Rigshospitalet. Project duration 2015-2019.
  12. Improving Patient Safety Through Online Treatment Monitoring in Brachytherapy. Erik Buch Jørgensen. Aarhus University Hospital. Project duration 2018-2021. PhD defence November 12 2021.
  13. Comparison of radiation treatment plans, for patient selection and establishment of best practices. Laura Kaplan. Aarhus University Hospital. Project duration 2018-2021. PhD defence November 28 2021.
  14. Morbidity after treatment for brain tumours. Lene Haldbo-Classen. Aarhus University Hospital. Project duration 2017-2020. PhD defence January 22 2021.
  15. Early mortality after radical radiotherapy. Kristian Hastoft Jensen. Rigshospitalet. Project duration 2019-2022.
  16. Immuno-radiotherapy for metastatic castration-resistant prostate cancer. Nicklas Juel Spindler. Herlev and Gentofte Hospital. Project duration 2020-2023.
  17. Preclinical RBE for normal tissue damage established in in vivo models. Cathrine Overgaard. Aarhus University Hospital. Project duration 2019-2023.
  18. Characterization of patient specific PTV based on multiple MRI scans before and during treatment to obtain adaptive treatment strategy for dose escalation. Dennis Tideman Arp. Aalborg University Hospital. Project duration 2019-2022.
  19. Towards improved chemo-radiotherapy for squamous cell carcinomas of the anus, by targeting the molecular biological features. Anna Cecilie Lefevre. Aarhus University Hospital. Project duration 2019-2022.
  20. Shared Decision Making for Breast Cancer Patients – with a main focus on adjuvant radiotherapy. Stine Rauff Søndergaard. Lillebælt Hospital, Vejle and University of Southern Denmark. Project duration 2019-2022.
  21. Respiratory gated photon and proton radiotherapy guided by internal tumor motion monitoring with conventional standard imager systems. Casper Muurholm Gammelmark. Aarhus University Hospital. Project duration 2018-2021.
  22. Three-dimensional dose measurements of proton therapy for tumour sites influenced by internal organ motion in human-like phantoms. Simon Heebøl Vindbæk. Aarhus University Hospital. Project duration 2019-2022. PhD defence December 15 2022.
  23. Optimal individual treatment strategy for every locally advanced non-small cell lung cancer patient. Marie Tvilum Hede. Aarhus University Hospital. Project duration 2019-2023. PhD defence November 3 2023.
  24. Stereotactic ablative radiotherapy for patients with oligometastatic disease. Mette Felter. Herlev Hospital. Project duration 2019-2022. PhD defence September 15 2023.
  25. Deep learning for improved tumour delineation in radiotherapy of head and neck cancer. Jintao Ren. Aarhus University Hospital. Project duration 2019-2023. PhD defence September 5 2023.
  26. Real-time reconstruction of the dose delivered to moving anatomy during radiotherapy with an MR-linac. Andreas Hagner. Aarhus University Hospital. Project duration 2020-2023. 
  27. Individualized robustness in treatment planning for head and neck proton radiotherapy. Raul Argota-Perez. Aarhus University Hospital. Project duration 2018-2021. PhD defence May 25 2023.
  28. Radiation therapy of sinonasal cancer. Maja B. Sharma. Aarhus University Hospital. Project duration 2017-2020. PhD defence December 10 2021.
  29. Treatment failure in squamous cell carcinoma of the anus – real-world data and biological features of recurrences. Karen Lycke Wind. Aarhus University Hospital. Project duration 2020-2023.
  30. Investigating geometric distortions in MRI used for radiotherapy: A national studySigne Winther Hasler. Odense University Hospital. Project duration 2020-2023. PhD defence March 8 2024.
  31. Deep learning for medical image segmentation and registry-based analysis of dose-effect for normal tissue damage in radiotherapy. Abraham George Smith. Rigshospitalet. Project duration 2020-2023.
  32. New planning concept for online adaptive and online monitored MR-linac radiotherapy. Isak Wahlstedt. Rigshospitalet. Project duration 2020-2023. PhD defence April 25 2023.
  33. Biological identification of recurrence after curative intended radiotherapy for carcinoma of the head and neck. A DAHANCA 19 study. Morten Horsholt Kristensen. Aarhus University Hospital. Project duration 2020-2023.
  34. Risk of cardiovascular disease after cancers of the lung and esophagus treated with definitive radiotherapy. Agon Olloni. Odense University Hospital. Project duration 2020-2023.
  35. Metastatic presentation of squamous cell carcinoma of the pharynx and larynx. Julie Kjems. Rigshospitalet. Project duration 2019-2023.
  36. Dosimetry for online monitored MR linac radiotherapy. Mads Fjelbro Klavsen. DTU Health Tech. Project duration 2019-2022.
  37. Development of Quantitative Magnetic Resonance Imaging (qMRI) Methods for Radiotherapy Response Studies. Sofie Rahbek. DTU Health Tech. Project duration 2018-2021.
  38. Enhancing the Utilisation of In Vivo Dosimetry for Low-Energy Radiotherapy. Peter Georgi. Aarhus University Hospital. Project duration 2021-2023. PhD defence November 10 2023.
  39. DBCG RT Nation: Mapping the clinical gain and risk factors of radiotherapy treatment of breast cancer through big data analysis. Lasse Refsgaard. Aarhus University Hospital. Project duration 2019-2022.
  40. Enabling safe delivery of proton FLASH therapy using an ultra-fast in vivo dosimetry system. Eleni Kanouta. Aarhus University Hospital. Project duration 2020-2023. PhD defence October 27 2023.
  41. Individualized treatment margins through improved proton range uncertainty estimations. Ivanka Sojat Tarp. Aarhus University Hospital. Project duration 2021-2023.
  42. Development of a complex intervention to reduce barriers in clinical trial participation and radiotherapy among Danish patients with head and neck cancer. Anne Wilhøft Kristensen. Aarhus University Hospital. Project duration 2020-2025.
  43. Association between tumor immune response and risk of recurrence in breast cancer patients treated with radiotherapy. Demet Özcan. Aarhus University Hospital. Project duration 2021-2024.
  44. DBCG RT Nation Automation. Emma Riis Skarsø. Aarhus University Hospital. Project duration 2021-2024.
  45. DW-MRI as a decision making tool in the in-room, MRI guided radiotherapy pipeline. Anne Bisgaard. Odense University Hospital. Project duration 2020-2023. PhD defence October 27 2023.
  46. Robust optimization for anatomical variations in proton therapyNadine Vatterodt. Aarhus University Hospital. Project duration 2021-2024.
  47. Expanding the use of optimal radiotherapy planning and image guided treatment delivery in children and adolescents. Daniella Østergaard. Rigshospitalet/University of Copenhagen. Project duration 2022-2025.
  48. ESO-SPARE- Esophagus sparing radiotherapy for thoracic and cervical metastatic spinal cord compression. A randomized phase III study. Anna Mann Nielsen. Herlev and Gentofte Hospital. Project duration 2020-2024.
  49. Investigating the use of artificial intelligence for daily CBCT-guided online adaptive radiotherapy. Lina Andersson. Herlev and Gentofte Hospital/DTU Health Tech. Project duration 2020-2024
  50. Adaptive RT for Bladder and anal cancer patients. Katrine Smedegaard Storm. Herlev and Gentofte Hospital. Project duration 2021-2024
  51. Real-time motion-including dose reconstruction performed during radiotherapy treatment delivery. Simon Skouboe. Danish Centre for Particle Therapy, Aarhus University Hospital.  PhD defence January 16 2020.
  52. An interdisciplinary investigation of the use and benefit of auto-contouring. Mathis Ersted Rasmussen. Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2021-2024.
  53. Overcoming organ motion challenges within a national randomized clinical trial on proton therapy for locally advanced prostate cancer. Sofie Tilbæk. Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2021-2024.
  54. Reduction in healthy tissue irradiation in radiotherapy through risk-based differentiation of target dose-volumes. Kristoffer Moos. Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2022-2025.
  55. Monitoring of individual patient doses for improved interpretation of clinical trials in radiation therapy of cancer. Karolina Alexandra Klucznik. Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2022-2025.
  56. Towards clinical application of radiochromic 3D dosimetry for radiotherapy verification in combined magnetic resonance imaging and linear accelerator systems. Morten Bjørn Jensen. Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2019-2023.
  57. Quantifying and reducing doses to brain structures associated with cognition following cranial irradiation of childhood cancer through the use of proton therapy. Laura Toussaint. Danish Centre for Particle Therapy, Aarhus University Hospital. PhD defence June 2, 2020.
  58. Patient-centered use of stereotactic body radiation therapy for lung cancer. Thomas Leth Fink, Vejle Hospital. Project duration 2020-2023.
  59. Improving evidence-based health care using artificial intelligence. Camilla Panduro Nielsen. University of Southern Denmark. Project duration 2022-2025.
  60. Heritable retinoblastoma in Denmark. Pernille Gregersen. Aarhus University. Project duration 2019-2022.
  61. Techniques for improvement of on-board imaging. Mikkel Skaarup. Rigshospitalet.
  62. The Immune Effect of Radiotherapy on Infectious Complications in Cancer Patients. Cynthia Campos. Rigshospitalet.
  63. Expanding non-parametric survival methods in radiotherapy using variable extraction from medical image analysis. Nora Forbes. Rigshospitalet.
  64. Hodgkin lymphoma survivorship: Past, present and future. Sidsel Jacobsen Juul. Rigshospitalet.
  65. Automated Adaptive Radiotherapy to improve head and neck cancer treatment. Anne Marie Lindegaard. Rigshospitalet.
  66. Irradiation to internal mammary nodes in 4843 high-risk breast cancer patients in the era of modern adjuvant therapy: The nationwide prospective DBCG IMN2 study. Anders Winther Mølby Nielsen. Aarhus University Hospital. Project duration 2021-2024.
  67. Optimized radiotherapy for primary and recurrent rectal cancer. Christina Truelsen. Danish Centre for Particle Therapy and Experimental Clinical oncology, Aarhus University Hospital. Project duration 2022-2024.
  68. Improving the image-basis for proton therapy dose calculations through deep learning. Casper Dueholm Vestergaard. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2022-2025.
  69. Identifying the optimal combination of hyperthermia with photon-based stereotactic radiotherapy to produce the most effective cancer treatment. Folefac Charlemagne Asonganyi. Aarhus University Hospital. Project duration 2021-2024.
  70. Development of physics-based proton therapy dose response models to reduce normal tissue complications within a randomised clinical trial for prostate cancer patients. Rasmus Klitgaard. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2021-2024.
  71. Combined Deep learning and Advanced Imaging for Improved Individualized Radiotherapy Target Definition in Glioblastoma Patients. A National DNOG study. Kim Hochreuter. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2021-2024.
  72. Optimal Proton Therapy for Pediatric Posterior Fossa Tumors. Peter Magnus Trock Lægdsmand. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration 2022-2025.
  73. Dose delivery verification during brachytherapy with scintillator detectors. Marjolein Louise E Heidotting. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2022-2025.
  74. Experimental radiobiology for different radiation modalities. Line Kristensen. The Danish Centre for Particle Therapy and Experimental Clinical Oncology, Aarhus University Hospital. Project duration: 2023-2026.
  75. Enabling safe delivery of proton and electron FLASH therapy using an ultra-fast in vivo dosimetry system. Sky Rohrer. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2023-2025.
  76. Exercise in combination with chemo-, anti-IL-6-receptor antibody, immune- and radiotherapy as a new anti-tumor strategy against pancreatic cancer. Mie Marienhof Krøyer von Staffeldt. Herlev Hospital.
  77. Combining proton irradiation with hyperthermia to improve cancer therapy. Priyanshu M. Sinha. Aarhus University Hospital. Project duration: 2021-2024.
  78. Deep learning for auto segmentation and dose prediction in the brain. Anne Haahr Andresen. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2022-2025.
  79. Proton minibeam radiotherapy. Fardous Reaz. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2022-2024.
  80. A three-dimensional spectral microCT imaging: an online tool for tumor surgery evaluation. Imaiyan Chitra Ragupathy. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2021-2024.
  81. Simon Nyberg Thomsen. (Title upcoming). Aarhus University Hospital.
  82. Elucidating the Role of Secondary Particles in Proton Therapy. Villads Lundsteen Jacobsen. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2022-2025.
  83. Interactive deep learning-based tumor segmentation for radiotherapy. Zixiang (Alan) Wei. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2021-2023.
  84. Reduction of dose to normal tissue in patients with head and neck cancer using adaptive proton therapy. Ihsan Bahij. The Danish Centre for Particle Therapy, Aarhus University Hospital. Project duration: 2022-2025.
  85. Outcome-based multiobjective optimisation of lymphoma radiotherapy plans using machine learning. Denis Kútnar. Rigshospitalet. Project duration: November 2022-2025.