Ludvig Muren

Professor Department of Oncology, Aarhus University Hospital ludvmure@rm.dk
Research interests Workgroups Publications
  • Toussaint L, Indelicato DJ, Muren LP, Li Z, Lassen-Ramshad Y, Kirby K, Pedro C, Mikkelsen R, Di Pinto M, Høyer M, Stokkevåg CH. Temporal lobe sparing radiotherapy with photons or protons for cognitive function preservation in paediatric craniopharyngioma Radiother Oncol . 2020 Jan;142:140-146 2020
  • Jensen SV, Valdetaro LB, Poulsen PR, Balling P, Petersen JBB, Muren LP Dose-response of deformable radiochromic dosimeters for spot scanning proton therapy Phys Imaging Radiat Oncol. 2020 Nov 20;16:134-137 2020
  • Pedersen J, Flampouri S, Bryant C, Liang X, Mendenhall N, Li Z, Liu M, Muren LP. Cross-modality applicability of rectal normal tissue complication probability models from photon- to proton-based radiotherapy. Radiother Oncol. 2020 Jan;142:253-260 2020
  • Toussaint L, Indelicato DJ, Stokkevåg CH, Lassen-Ramshad Y, Pedro C, Mikkelsen R, Di Pinto M, Li Z, Flampouri S, Vestergaard A, Petersen JBB, Schrøder H, Høyer M, Muren LP Radiation doses to brain substructures associated with cognition in radiotherapy of pediatric brain tumors. Acta Oncol. 2019 Oct;58(10):1457-1462. 2019
  • Overgaard J, Muren LP, Høyer M, Grau C BIGART 2019 - adapting to the future. Acta Oncol. 2019 Oct;58(10):1323-1327. 2019
  • Busch K, Andersen AG, Petersen JBB, Petersen SE, Rønde HS, Bentzen L, Pilskog S, Skyt P, Nørrevang O, Muren LP Towards range-guidance in proton therapy to detect organ motion-induced dose degradations Biomed Phys Eng Express . 2022 Feb 18;8(2) 2022
  • Petersen SE, Thorsen LB, Hansen S, Petersen PM, Lindberg H, Moe M, Petersen JB, Muren LP, Høyer M, Bentzen L A phase I/II study of acute and late physician assessed and patient-reported morbidity following whole pelvic radiation in high-risk prostate cancer patients Acta Oncol . 2022 Feb;61(2):179-184 2022
  • Valdetaro LB, Høye EM, Skyt PS, Petersen JBB, Balling P, Muren LP Empirical quenching correction in radiochromic silicone-based three-dimensional dosimetry of spot-scanning proton therapy Phys Imaging Radiat Oncol . 2021 Apr 12;18:11-18 2021
  • Toussaint L, Peters S, Mikkelsen R, Karabegovic S, Bäumer C, Muren LP, Tram-Henriksen L, Høyer M, Lassen-Ramshad Y, Timmermann B Delineation atlas of the Circle of Willis and the large intracranial arteries for evaluation of doses to neurovascular structures in pediatric brain tumor patients treated with radiation therapy Acta Oncol . 2021 Nov;60(11):1392-1398 2021
  • Busch K, Dahl B, Petersen SE, Rønde HS, Bentzen L, Pilskog S, Muren LP Anatomically robust proton therapy using multiple planning computed tomography scans for locally advanced prostate cancer Acta Oncol . 2021 May;60(5):598-604 2021
  • Busch K, Muren LP, Thörnqvist S, Andersen AG, Pedersen J, Dong L, Petersen JBB On-line dose-guidance to account for inter-fractional motion during proton therapy Phys Imaging Radiat Oncol. 2018 Dec 19;9:7-13 2018
  • Casares-Magaz O, Muren LP, Pettersson N, Thor M, Hopper A, Knopp R, Deasy JO, Væth M, Einck J, Moiseenko V A case-control study using motion-inclusive spatial dose-volume metrics to account for genito-urinary toxicity following high-precision radiotherapy for prostate cancer. Phys Imaging Radiat Oncol. 2018 Oct 5;7:65-69 2018
  • Casares-Magaz O, Raidou RG, Rørvik J, Vilanova A, Muren LP. Uncertainty evaluation of image-based tumour control probability models in radiotherapy of prostate cancer using a visual analytic tool Phys Imaging Radiat Oncol. 2018 Jan 12;5:5-8 2018
  • Clark CH, Jornet N, Muren LP The role of dosimetry audit in achieving high quality radiotherapy. Phys Imaging Radiat Oncol. 2018 Mar 21;5:85-87 2018
  • Hysing LB, Ekanger C, Zolnay Á, Helle SI, Rasi M, Heijmen BJM, Sikora M, Söhn M, Muren LP, Thörnqvist S Statistical motion modelling for robust evaluation of clinically delivered accumulated dose distributions after curative radiotherapy of locally advanced prostate cancer Radiother Oncol. 2018 Aug;128(2):327-335 2018
  • Losnegård A, Reisæter L, Halvorsen OJ, Beisland C, Castilho A, Muren LP, Rørvik J, Lundervold A Intensity-based volumetric registration of magnetic resonance images and whole-mount sections of the prostate Comput Med Imaging Graph. 2018 Jan;63:24-30 2018
  • Muren LP. The first year achievements of Physics and Imaging in Radiation Oncology Phys Imaging Radiat Oncol. 2018 Apr 7;5:111-112 2018
  • Pedersen J, Casares-Magaz O, Petersen JBB, Rørvik J, Bentzen L, Andersen AG, Muren LP. A biological modelling based comparison of radiotherapy plan robustness using photons vs protons for focal prostate boosting. Imaging Radiat Oncol. 2018 Jul 18;6:101-105 2018
  • Taasti VT, Bäumer C, Dahlgren CV, Deisher AJ, Ellerbrock M, Free J, Gora J, Kozera A, Lomax AJ, De Marzi L, Molinelli S, Kevin Teo BK, Wohlfahrt P, Petersen JBB, Muren LP, Hansen DC, Richter C. Inter-centre variability of CT-based stopping-power prediction in particle therapy: Survey-based evaluation. Phys Imaging Radiat Oncol. 2018 Apr 30;6:25-30 2018
  • Taasti VT, Hansen DC, Michalak GJ, Deisher AJ, Kruse JJ, Muren LP, Petersen JBB, McCollough CH. Theoretical and experimental analysis of photon counting detector CT for proton stopping power prediction Med Phys. 2018 Nov;45(11):5186-5196 2018
  • Taasti VT, Muren LP, Jensen K, Petersen JBB, Thygesen J, Tietze A, Grau C, Hansen DC Comparison of single and dual energy CT for stopping power determination in proton therapy of head and neck cancer. Phys Imaging Radiat Oncol. 2018 Apr 22;6:14-19 2018
  • Casares-Magaz O, Bülow S, Pettersson NJ, Moiseenko V, Pedersen J, Thor M, Einck J, Hopper A, Knopp R, Muren LP High accumulated doses to the inferior rectum are associated with late gastro-intestinal toxicity in a case-control study of prostate cancer patients treated with radiotherapy. Acta Oncol. 2019 Oct;58(10):1543-1546 2019
  • Clark CH, Gagliardi G, Heijmen B, Malicki J, Thorwarth D, Verellen D, Muren LP. Adapting training for medical physicists to match future trends in radiation oncology Phys Imaging Radiat Oncol. 2019 Sep 19;11:71-75 2019
  • Cozzi L, Heijmen BJM, Muren LP. Advanced treatment planning strategies to enhance quality and efficiency of radiotherapy Phys Imaging Radiat Oncol. 2019 Sep 13;11:69-70. 2019
  • Mancosu P, Cozzi L, Muren LP. Total marrow irradiation for hematopoietic malignancies using volumetric modulated arc therapy: A review of treatment planning studies. Phys Imaging Radiat Oncol. 2019 Aug 29;11:47-53 2019
  • Stokkevåg CH, Indelicato DJ, Herfarth K, Magelssen H, Evensen ME, Ugland M, Nordberg T, Nystad TA, Hægeland C, Alsaker MD, Ulven K, Dale JE, Engeseth GM, Boer CG, Toussaint L, Kornerup JS, Pettersen HES, Brydøy M, Brandal P, Muren LP Normal tissue complication probability models in plan evaluation of children with brain tumors referred to proton therapy Acta Oncol. 2019 Oct;58(10):1416-1422 2019
  • Thorwarth D, Muren L Imaging science and development in modern high-precision radiotherapy Phys Imaging Radiat Oncol. 2019 Dec 9;12:63-66 2019
  • Toussaint L, Indelicato DJ, Holgersen KS, Petersen JBB, Stokkevåg CH, Lassen-Ramshad Y, Casares-Magaz O, Vestergaard A, Muren LP Towards proton arc therapy: physical and biologically equivalent doses with increasing number of beams in pediatric brain irradiation Acta Oncol. 2019 Oct;58(10):1451-1456 2019
  • Andersen AG, Park YK, Elstrøm UV, Petersen JBB, Sharp GC, Winey B, Dong L, Muren LP Evaluation of an a priori scatter correction algorithm for cone-beam computed tomography based range and dose calculations in proton therapy Phys Imaging Radiat Oncol. 2020 Oct 27;16:89-94. doi: 10.1016/j.phro.2020.09.014 2019
  • Casares-Magaz O, Moiseenko V, Witte M, Rancati T, Muren LP Towards spatial representations of dose distributions to predict risk of normal tissue morbidity after radiotherapy Phys Imaging Radiat Oncol. 2020 Aug 28;15:105-107 2020
  • Fiorino C, Jeraj R, Clark CH, Garibaldi C, Georg D, Muren L, van Elmpt W, Bortfeld T, Jornet N Grand challenges for medical physics in radiation oncology Radiother Oncol. 2020 Dec;153:7-14 2020
  • Fjæra LF, Indelicato DJ, Stokkevåg CH, Muren LP, Hsi WC, Ytre-Hauge KS Implementation of a double scattering nozzle for Monte Carlo recalculation of proton plans with variable relative biological effectiveness. Phys Med Biol. 2020 Nov 19;65(22) 2020
  • Fjæra LF, Indelicato DJ, Ytre-Hauge KS, Muren LP, Lassen-Ramshad Y, Toussaint L, Dahl O, Stokkevåg CH Spatial Agreement of Brainstem Dose Distributions Depending on Biological Model in Proton Therapy for Pediatric Brain Tumors Adv Radiat Oncol. 2020 Aug 28;6(1):100551 2020
  • Jensen MB, Balling P, Doran SJ, Petersen JBB, Wahlstedt IH, Muren LP Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field. Phys Imaging Radiat Oncol. 2020 Oct 19;16:81-84 2020
  • Pedersen J, Liang X, Casares-Magaz O, Bryant C, Mendenhall N, Li Z, Muren LP Multivariate normal tissue complication probability models for rectal and bladder morbidity in prostate cancer patients treated with proton therapy Radiother Oncol. 2020 Dec;153:279-288 2020
  • Taasti VT, Klages P, Parodi K, Muren LP Developments in deep learning based corrections of cone beam computed tomography to enable dose calculations for adaptive radiotherapy Phys Imaging Radiat Oncol. 2020 Aug 12;15:77-79. 2020
  • Bertholet J, Aznar MC, Garibaldi C, Thwaites D, Gershkevitsh E, Thorwarth D, Verellen D, Heijmen B, Hurkmans C, Muren L, Redalen KR, Siebert FA, Schwarz M, Van Elmpt W, Georg D, Jornet N, Clark CH Professional practice changes in radiotherapy physics during the COVID-19 pandemic Phys Imaging Radiat Oncol. 2021 Jul;19:25-32 2021
  • Mancosu P, Navarria P, Muren LP, Castagna L, Reggiori G, Clerici E, Sarina B, Bramanti S, De Philippis C, Tomatis S, Santoro A, Scorsetti M Development of an Immobilization Device for Total Marrow Irradiation Pract Radiat Oncol. 2021 Jan-Feb;11(1):e98-e105 2021
  • Otterlei OM, Indelicato DJ, Toussaint L, Ytre-Hauge KS, Pilskog S, Fjaera LF, Rørvik E, Pettersen HES, Muren LP, Lassen-Ramshad Y, Di Pinto M, Stokkevåg CH Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors Acta Oncol. 2021 Feb;60(2):267-274 2021
  • Pedersen J, Liang X, Bryant C, Mendenhall N, Li Z, Muren LP Normal tissue complication probability models for prospectively scored late rectal and urinary morbidity after proton therapy of prostate cancer Phys Imaging Radiat Oncol. 2021 Nov 8;20:62-68 2021
  • Peters N, Muren LP Towards an integral clinical proton dose prediction uncertainty by considering delineation variation Phys Imaging Radiat Oncol. 2022 Mar 5;21:134-135 2022
  • Muren LP, Redalen KR, Thorwarth D Five years, 20 volumes and 300 publications of Physics and Imaging in Radiation Oncology Phys Imaging Radiat Oncol. 2022 Mar 3;21:123-125 2022
  • Jensen SV, Muren LP, Balling P, Petersen JB, Valdetaro LB, Poulsen PR Dose perturbations in proton pencil beam delivery investigated by dynamically deforming silicone-based radiochromic dosimeters Phys Med Biol. 2022 Nov 25;67(23) 2022
  • Jensen MB, B Valdetaro L, Balling P, Skyt PS, Petersen JBB, Doran SJ, Sitarz MK, Muren LP . Impact of curing conditions on basic dosimetric properties of silicone-based radiochromic dosimeters for photon and proton irradiation Acta Oncol. 2022 Feb;61(2):264-268 2022
  • Fjæra LF, Indelicato DJ, Handeland AH, Ytre-Hauge KS, Lassen-Ramshad Y, Muren LP, Stokkevåg CH A case-control study of linear energy transfer and relative biological effectiveness related to symptomatic brainstem toxicity following pediatric proton therapy Radiother Oncol. 2022 Oct;175:47-55 2022