Research interests
Workgroups
Publications
- Hypofractionated Versus Standard Fractionated Radiotherapy in Patients With Early Breast Cancer or Ductal Carcinoma In Situ in a Randomized Phase III Trial: The DBCG HYPO Trial J Clin Oncol. 2020 Nov 1;38(31):3615-3625 2020
- Breast cancer radiation therapy Lancet . 2020 Nov 14;396(10262):1558 2020
- Does the combination of hyperthermia with low LET (linear energy transfer) radiation induce anti-tumor effects equivalent to those seen with high LET radiation alone? Int J Hyperthermia . 2021;38(1):105-110 2021
- Correlation and prognostic impact of human papilloma virus and p16-expression in advanced hypopharynx and larynx cancer treated with definitive radiotherapy Acta Oncol . 2021 May;60(5):646-648 2021
- Distant metastases in squamous cell carcinoma of the pharynx and larynx: a population-based DAHANCA study Acta Oncol. 2021 Nov;60(11):1472-1480 2021
- Hypoxic gene expression is a prognostic factor for disease free survival in a cohort of locally advanced squamous cell cancer of the uterine cervix Acta Oncol . 2022 Feb;61(2):172-178 2022
- Tumor-infiltrating lymphocytes predict improved overall survival after post-mastectomy radiotherapy: a study of the randomized DBCG82bc cohort Acta Oncol . 2022 Feb;61(2):153-162 2022
- No time to die - BiGART is back. The 20th Acta Oncologica Symposium - BIGART 2021 Acta Oncol . 2022 Feb;61(2):117-119 2022
- A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis Br J Cancer . 2022 Apr;126(7):1082-1090 2022
- Personalised radiation therapy taking both the tumour and patient into consideration Radiother Oncol . 2022 Jan;166:A1-A5 2022
- Postmastectomy radiotherapy in high-risk breast cancer patients given adjuvant systemic therapy. A 30-year long-term report from the Danish breast cancer cooperative group DBCG 82bc trial Radiother Oncol . 2022 May;170:4-13 2022
- Internal Mammary Node Irradiation in Patients With Node-Positive Early Breast Cancer: Fifteen-Year Results From the Danish Breast Cancer Group Internal Mammary Node Study J Clin Oncol . 2022 Apr 8 2022
- Hypoxia and local tumour control in squamous cell carcinoma of the anus - a hypothesis-generating study Acta Oncol . 2022 Jun 22;1-4 2022
- Partial Breast Irradiation Versus Whole Breast Irradiation for Early Breast Cancer Patients in a Randomized Phase III Trial: The Danish Breast Cancer Group Partial Breast Irradiation Trial J Clin Oncol . 2022 Aug 5 2022
- Treatment outcomes and survival following definitive (chemo)radiotherapy in HPV-positive oropharynx cancer: Large-scale comparison of DAHANCA vs PMH cohorts Int J Cancer . 2022 Apr 15;150(8):1329-1340 2022
- Target coverage and local recurrences after radiotherapy for sinonasal cancer in Denmark 2008-2015. A DAHANCA study Acta Oncol . 2022 Feb;61(2):120-126 2022
- Bloodstream infections in head and neck cancer patients after curative-intent radiotherapy: a population-based study from the Danish Head and Neck Cancer Group database Br J Cancer. 2021 Aug;125(3):458-464 2021
- Investigating the potential of deep learning for patient-specific quality assurance of salivary gland contours using EORTC-1219-DAHANCA-29 clinical trial data Acta Oncol. 2021 Jan 11:1-7. 2021
- Radiation oncology in the new virtual and digital era Radiother Oncol. 2020 Dec 30:S0167-8140(20)31258-5. 2021
- Hypofractionated Versus Standard Fractionated Radiotherapy in Patients With Early Breast Cancer or Ductal Carcinoma In Situ in a Randomized Phase III Trial: The DBCG HYPO Trial J Clin Oncol. 2020 Nov 1;38(31):3615-3625. 2020
- Imaging of Tumor Hypoxia for Radiotherapy: Current Status and Future Directions Semin Nucl Med. 2020 Nov;50(6):562-583. 2020
- Incidence and Mortality of Second Primary Cancers in Danish Patients With Retinoblastoma, 1943-2013 JAMA Netw Open. 2020 Oct 1;3(10):e2022126. 2020
- DAHANCA 33: functional image-guided dose-escalated radiotherapy to patients with hypoxic squamous cell carcinoma of the head and neck (NCT02976051) Acta Oncol. 2020 Feb;59(2):208-211 2020
- What will radiation oncology look like in 2050? A look at a changing professional landscape in Europe and beyond Mol Oncol. 2020 Jul;14(7):1577-1585. 2020
- Prognostic impact of PD-L1 in oropharyngeal cancer after primary curative radiotherapy and relation to HPV and tobacco smoking. Acta Oncol. 2020 Jun;59(6):666-672. 2020
- The danish head and neck cancer group (DAHANCA) 2020 radiotherapy guidelines. Radiother Oncol. 2020 Aug 8;151:149-151. 2020
- Influence of FAZA PET hypoxia and HPV-status for the outcome of head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy: Long-term results from the DAHANCA 24 trial (NCT01017224). Radiother Oncol. 2020 Aug 14;151:126-133. 2020
- Early Mortality after Radical Radiotherapy in Head and Neck Cancer - A Nationwide Analysis from the Danish Head and Neck Cancer Group (DAHANCA) Database. Clin Oncol (R Coll Radiol) . 2020 Jul 19;S0936-6555(20)30286-7. 2020
- Characterization and radiosensitivity of HPV-related oropharyngeal squamous cell carcinoma patient-derived xenografts. Acta Oncol. 2019 Oct;58(10):1489-1494. 2019
- A prospective, multicenter DAHANCA study of hyperfractionated, accelerated radiotherapy for head and neck squamous cell carcinoma. Acta Oncol. 2019 Oct;58(10):1495-1501. 2019
- Distinguishing recurrence and new primary tumor as well as the origin of neck metastases in head and neck cancer clinical trials by targeted DNA sequencing. Acta Oncol. 2019 Oct;58(10):1506-1508. 2019
- Dual-tracer PET of viable tumor volume and hypoxia for identification of necrosis-containing radio-resistant Sub-volumes. Acta Oncol. 2019 Oct;58(10):1476-1482. 2019
- IMRT - Biomarkers for dose escalation, dose de-escalation and personalized medicine in radiotherapy for head and neck cancer. Oral Oncol. 2018 Nov;86:91-99. 2018
- Local recurrences after curative IMRT for HNSCC: Effect of different GTV to high-dose CTV margins. Radiother Oncol. 2018 Jan;126(1):48-55. 2018
- NTCP model validation method for DAHANCA patient selection of protons versus photons in head and neck cancer radiotherapy. Acta Oncol. 2019 Oct;58(10):1410-1415. 2019
- Hyperthermia: The Optimal Treatment to Overcome Radiation Resistant Hypoxia. Cancers (Basel). 2019 Jan 9;11(1). 2019
- Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials. Acta Oncol. 2018 Jan;57(1):38-43 2018
- Influence of intra-tumoral heterogeneity on the evaluation of BCL2, E-cadherin, EGFR, EMMPRIN, and Ki-67 expression in tissue microarrays from breast cancer. Acta Oncol. 2018 Jan;57(1):102-106. 2018
- Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial. Acta Oncol. 2018 Sep;57(9):1159-1164 2018
- BIGART 2019 - adapting to the future. Acta Oncol. 2019 Oct;58(10):1323-1327. 2019
- Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer. Radiother Oncol. 2022 Sep 30;176:138-148 2022
- Forty years of landmark trials undertaken by the Danish Breast Cancer Cooperative Group (DBCG) nationwide or in international collaboration Acta Oncol. 2018 Jan;57(1):3-12 2018
- APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells. Cell Chem Biol. 2018 Nov 15;25(11):1337-1349.e12 2018
- Prognostic impact of HPV-associated p16-expression and smoking status on outcomes following radiotherapy for oropharyngeal cancer: The MARCH-HPV project. Radiother Oncol. 2018 Jan;126(1):107-115 2018
- The management and survival outcomes of nasopharyngeal cancer in the Nordic countries Acta Oncol. 2018 Apr;57(4):557-560. 2018
- DAHANCA 10 - Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and neck cancer group. Radiother Oncol. 2018 Apr;127(1):12-19 2018
- RE: Hypofractionated Radiotherapy for Patients with Early-Stage Glottic Cancer: Patterns of Care and Survival. J Natl Cancer Inst. 2018 Apr 1;110(4):430-431 2018
- DAHANCA 9 - a randomized multicenter study to compare accelerated normo-fractionated radiotherapy with accelerated hyperfractionated radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC) Acta Oncol. 2019 Oct;58(10):1502-1505 2019
- Subglottic squamous cell carcinoma in Denmark 1971-2015 - a national population-based cohort study from DAHANCA, the Danish Head and Neck Cancer group. Acta Oncol. 2019 Oct;58(10):1509-1513 2019
- Repeat FMISO-PET imaging weakly correlates with hypoxia-associated gene expressions for locally advanced HNSCC treated by primary radiochemotherapy. Radiother Oncol. 2019 Jun;135:43-50 2019
- Effect of ESA as a modifier of radiotherapy in curative intended treatment of squamous cell carcinoma of the head and neck (HNSCC) Radiother Oncol. 2019 Jan;130:191-192 2019
- Analysis of EORTC-1219-DAHANCA-29 trial plans demonstrates the potential of knowledge-based planning to provide patient-specific treatment plan quality assurance Radiother Oncol. 2019 Jan;130:75-81 2019
- What will radiation oncology look like in 2050? A look at a changing professional landscape in Europe and beyond Mol Oncol. 2020 Jul;14(7):1577-1585 2020
- Radiotherapy & Oncology during the COVID-19 pandemic Radiother Oncol. 2020 May;146:221-222. 2020
- Prognostic value of a 15-gene hypoxia classifier in oropharyngeal cancer treated with accelerated chemoradiotherapy Strahlenther Onkol. 2020 Jun;196(6):552-560 2020
- Four decades with ESTRO Radiother Oncol. 2020 Jan;142:1-5 2020
- DAHANCA 28: A phase I/II feasibility study of hyperfractionated, accelerated radiotherapy with concomitant cisplatin and nimorazole (HART-CN) for patients with locally advanced, HPV/p16-negative squamous cell carcinoma of the oropharynx, hypopharynx, larynx and oral cavity Radiother Oncol. 2020 Jul;148:65-72 2020
- Predictive classifier for intensive treatment of head and neck cancer Cancer. 2020 Dec 15;126(24):5263-5273 2020
- Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy Radiother Oncol. 2020 Aug;149:189-196 2020
- Danish Head & Neck Cancer group (DAHANCA) kvalitetsdatabase - Resumé af årsrapport 2020 Ugeskr Læg 2021. 2021
- Sinonasal cancer in Denmark 2008-2015: a population-based phase-4 cohort study from DAHANCA Acta Oncol. 2021 Mar;60(3):333-342 2021
- Living with heritable retinoblastoma and the perceived role of regular follow-up at a retinoblastoma survivorship clinic: 'That is exactly what I have been missing' BMJ Open Ophthalmol. 2021 Sep 12;6(1):e000760 2021
- Investigating the potential of deep learning for patient-specific quality assurance of salivary gland contours using EORTC-1219-DAHANCA-29 clinical trial data Acta Oncol. 2021 May;60(5):575-581 2021
- Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis Lancet Oncol. 2021 May;22(5):727-736 2021
- Independent external validation using the EORTC HNCG-ROG 1219 DAHANCA 29 trial data of NTCP models for acute oral mucositis Radiother Oncol. 161: 35-39, 2021 2021
- Volume matters: Breast induration is associated with irradiated breast volume in the Danish Breast Cancer Group phase III randomized Partial Breast Irradiation trial Radiother Oncol. 2022 Dec;177:231-235 2022
- Association of Smoking, Comorbidity, Clinical Stage, and Treatment Intent With Socioeconomic Differences in Survival After Oropharyngeal Squamous Cell Carcinoma in Denmark JAMA Netw Open. 2022 Dec 1;5(12):e2245510 2022
- Breast cancer radiotherapy: Is it time to rethink the indication? Radiother Oncol. 2022 Dec;177:238-239 2022
- Biological modeling in thermoradiotherapy: present status and ongoing developments toward routine clinical use Int J Hyperthermia. 2022;39(1):1126-1140 2022
- Genetic testing in adult survivors of retinoblastoma in Denmark: A study of the experience and impact of genetic testing many years after initial diagnosis Eur J Med Genet. 2022 Sep;65(9):104569 2022
- Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1. Radiother Oncol. 2022 Jan;166:137-144 2022
- Nasal vestibule squamous cell carcinoma: a population-based cohort study from DAHANCA Acta Oncol. 2022 Feb;61(2):127-133 2022