Lone Hoffmann

PhD Department of Oncology, Aarhus University Hospital lone.hoffmann@aarhus.rm.dk
Research interests


  • Adaptiv radioterapi til lunge og esophaguscancer
  • Dosis eskalation til lunge og esophaguscancerpatienter
  • Functionel imaging til lungecancerpatienter
  • Intra og interfraktionelle forandringer
  • Gating til lunge og esophaguscancerpatienter
  • Protonterapi til lunge og esophagu cancer
  • Individualiseret RT
  • Optimal dosisplanlægning
  • Dosisplanlægningsalgorithmer


Workgroups Publications
  • Møller DS, Poulsen PR, Hagner A, Dufour M, Nordsmark M, Nyeng TB, Mortensen HR, Lutz CM, Hoffmann L Strategies for Motion Robust Proton Therapy With Pencil Beam Scanning for Esophageal Cancer Int J Radiat Oncol Biol Phys . 2021 Oct 1;111(2):539-548 2021
  • D. Sloth Møller, M.L. Schmidt, T. Ravkilde, P.R. Poulsen, J. Hansen, E.S. Worm, H.H. Schmidt, M.M. Knap, A. Safwat, H.K. Rose, L. Hoffmann Intra-fractional stability of deep inspiration breath hold during rt for lung and lymphoma cancer. Radiotherapy and Oncology Volume 133, Supplement 1, April 2019, Pages S531-S532 2019
  • Hoffmann L, Poulsen PR, Ravkilde T, Bertholet J, Kruhlikava I, Helbo BL, Schmidt ML, Nordsmark M. Setup strategies and uncertainties in esophageal radiotherapy based on detailed intra- and interfractional tumor motion mapping. Radiother Oncol. 2019 Jul;136:161-168. 2019
  • Møller DS, Alber M, Nordsmark M, Nyeng TB, Lutz CM, Hoffmann L Validation of a robust strategy for proton spot scanning for oesophageal cancer in the presence of anatomical changes. Radiother Oncol. pp. 131:174-178 2019
  • Schmidt ML, Hoffmann L, Møller DS, Knap MM, Rasmussen TR, Folkersen BH, Poulsen PR. Systematic intrafraction shifts of mediastinal lymph node targets between setup imaging and radiation treatment delivery in lung cancer patients. Radiother Oncol. 126 (2), pp. 318-324. 2018
  • Shamshad M, Møller DS, Mortensen HR, Ehmsen ML, Jensen MF, Hoffmann L Bone versus soft-tissue setup in proton therapy for patients with oesophageal cancer Acta Oncol . 2022 Jul 1;1-10 2022
  • Hoffmann L, Mortensen H, Shamshad M, Berbee M, Bizzocchi N, Bütof R, Canters R, Defraene G, Ehmsen ML, Fiorini F, Haustermans K, Hulley R, Korevaar EW, Clarke M, Makocki S, Muijs CT, Murray L, Nicholas O, Nordsmark M, Radhakrishna G, Thomas M, Troost EGC, Vilches-Freixas G, Visser S, Weber DC, Møller DS Treatment planning comparison in the PROTECT-trial randomising proton versus photon beam therapy in oesophageal cancer: Results from eight European centres Radiother Oncol . 2022 Jul;172:32-41 2022
  • Hoffmann L, Persson GF, Nygård L, Nielsen TB, Borrisova S, Gaard-Petersen F, Josipovic M, Khalil AA, Kjeldsen R, Knap MM, Kristiansen C, Møller DS, Ottosson W, Sand H, Thing R, Pøhl M, Schytte T Thorough design and pre-trial quality assurance (QA) decrease dosimetric impact of delineation and dose planning variability in the STRICTLUNG and STARLUNG trials for stereotactic body radiotherapy (SBRT) of central and ultra-central lung tumours Radiother Oncol . 2022 Jun;171:53-61 2022