Birgitte Vrou Offersen

Professor, MD Dept. of Experimental Clinical Oncology, Aarhus University Hospital Birgitte.Offersen@auh.rm.dk
Research interests Workgroups Publications
  • Aristei C, Kaidar-Person O, Tagliaferri L, Arenas M, Coles CE, Offersen BV, Frezza G, Leonardi MC, Valentini V, Bourgier C, Poortmans PMP The Assisi Think Tank Meeting and Survey of post MAstectomy Radiation Therapy after breast reconstruction Eur J Surg Oncol . 2018 Apr;44(4):436-443 2018
  • Martin Berg, Ebbe L Lorenzen, Ingelise Jensen, Mette S Thomsen, Christina Maria Lutz, Lasse Refsgaard, Henrik D Nissen , Birgitte V Offersen The potential benefits from respiratory gating for breast cancer patients regarding target coverage and dose to organs at risk when applying strict dose limits to the heart: results from the DBCG HYPO trial Acta Oncol. 2018 Jan;57(1):113-119 2018
  • Ejlertsen B, Offersen BV, Overgaard J, Christiansen P, Jensen MB, Kroman N, Knoop AS, Mouridsen H Forty years of landmark trials undertaken by the Danish Breast Cancer Cooperative Group (DBCG) nationwide or in international collaboration Acta Oncol. 2018 Jan;57(1):3-12 2018
  • Kirova YM, Carroll S, Fourquet A, Offersen B, Aristei C, Chen JY The St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2017: the point of view of an International Panel of Experts in Radiation Oncology. Ann Oncol. 2018 Jan 1;29(1):280-281 2018
  • Offersen BV, Ejlertsen B, Balslev E, Flyger H, Gerdes AM, Hansen MK, Hølmich LR, Jensen MB, Kristensen B, Laenkholm AV, Mouridsen HT, Nielsen MH, Overgaard J, Tuxen M, Vejborg I, Christiansen P. Is DBCG abreast of new developments? Acta Oncol. 2018 Jan;57(1):1-2. 2018
  • Begtrup KM, Hojbjerg JA, Offersen BV, Hvas AM Adjuvant radiotherapy does not affect hemostasis. Platelets. 2019;30(3):387-395 2019
  • Kaidar-Person O, Offersen BV, Poortmans P Should risk-adapted delineation considered de-escalation of therapy? The ESTRO-ACROP radiation therapy guidelines after implant-based immediate reconstruction for early stage breast cancer Radiother Oncol. 2019 Dec;141:327-328 2019
  • Montero-Luis A, Aristei C, Meattini I, Arenas M, Boersma L, Bourgier C, Coles C, Cutuli B, Falcinelli L, Kaidar-Person O, Leonardi MC, Offersen B, Marazzi F, Rivera S, Tagliaferri L, Tombolini V, Vidali C, Valentini V, Poortmans P The Assisi Think Tank Meeting Survey of post-mastectomy radiation therapy in ductal carcinoma in situ: Suggestions for routine practice Crit Rev Oncol Hematol. 2019 Jun;138:207-213 2019
  • Coles CE, Aristei C, Bliss J, Boersma L, Brunt AM, Chatterjee S, Hanna G, Jagsi R, Kaidar Person O, Kirby A, Mjaaland I, Meattini I, Luis AM, Marta GN, Offersen B, Poortmans P, Rivera S International Guidelines on Radiation Therapy for Breast Cancer During the COVID-19 Pandemic. Clin Oncol (R Coll Radiol). 2020 May;32(5):279-281 2020
  • Kaidar-Person O, Poortmans P, Offersen BV, Siesling S, Sklair-Levy M, Meattini I, de Ruysscher D, Kühn T, Boersma LJ Spatial location of local recurrences after mastectomy: a systematic review Breast Cancer Res Treat. 2020 Sep;183(2):263-273. 2020
  • Marta GN, Coles C, Kaidar-Person O, Meattini I, Hijal T, Zissiadis Y, Pignol JP, Ramiah D, Ho AY, Cheng SH, Sancho G, Offersen BV, Poortmans P The use of moderately hypofractionated post-operative radiation therapy for breast cancer in clinical practice: A critical review Crit Rev Oncol Hematol. 2020 Dec;156:103090 2020
  • Meattini I, Andratschke N, Kirby AM, Sviri G, Offersen BV, Poortmans P, Kaidar Person O Challenges in the treatment of breast cancer brain metastases: evidence, unresolved questions, and a practical algorithm Clin Transl Oncol. 2020 Oct;22(10):1698-1709 2020
  • Nordsmark M, Offersen BV The risk of radiation-associated heart disease comes from many factors; the chain is as strong as the weakest link Radiother Oncol. 2020 Nov;152:101-102 2020
  • Alstrup M, Johannessen AL, Mohanakumar S, Offersen BV, Hjortdal VE Lymphatic Function in the Arms of Breast Cancer Patients-A Prospective Cohort Study Plast Reconstr Surg Glob Open. 2021 Aug 25;9(8):e3779 2021
  • Dahn HM, Boersma LJ, de Ruysscher D, Meattini I, Offersen BV, Pignol JP, Aristei C, Belkacemi Y, Benjamin D, Bese N, Coles CE, Franco P, Ho A, Hol S, Jagsi R, Kirby AM, Marrazzo L, Marta GN, Moran MS, Nichol AM, Nissen HD, Strnad V, Zissiadis YE, Poortmans P, Kaidar-Person O The use of bolus in postmastectomy radiation therapy for breast cancer: A systematic review. Crit Rev Oncol Hematol. 2021 Jul;163:103391 2021
  • Kaidar-Person O, Dahn HM, Nichol AM, Boersma LJ, de Ruysscher D, Meattini I, Pignol JP, Aristei C, Belkacemi Y, Benjamin D, Bese N, Coles CE, Franco P, Ho AY, Hol S, Jagsi R, Kirby AM, Marrazzo L, Marta GN, Moran MS, Nissen HD, Strnad V, Zissiadis Y, Poortmans PM, Offersen BV A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer Radiother Oncol. 2021 Nov;164:115-121 2021
  • Kaidar-Person O, Hermann N, Poortmans P, Offersen BV, Boersma LJ, de Ruysscher D, Tramm T, Kühn T, Engberg Damsgaard T, Gentilini O, Maarse W, Sklair-Levi M, Mátrai Z A multidisciplinary approach for autologous breast reconstruction: A narrative (re)view for better management Radiother Oncol. 2021 Apr;157:263-271 2021
  • Kaidar-Person O, Offersen BV, Boersma L, Meattini I, Dodwell D, Wyld L, Aznar M, Major T, Kuehn T, Strnad V, Palmu M, Hol S, Poortmans P Tricks and tips for target volume definition and delineation in breast cancer: Lessons learned from ESTRO breast courses Radiother Oncol. 2021 Sep;162:185-194 2021
  • Kaidar-Person O, Offersen BV, Boersma LJ, de Ruysscher D, Tramm T, Kühn T, Gentilini O, Mátrai Z, Poortmans P A multidisciplinary view of mastectomy and breast reconstruction: Understanding the challenges Breast. 2021 Apr;56:42-52 2021
  • Marta GN, Ramiah D, Kaidar-Person O, Kirby A, Coles C, Jagsi R, Hijal T, Sancho G, Zissiadis Y, Pignol JP, Ho AY, Cheng SH, Offersen BV, Meattini I, Poortmans P. The Financial Impact on Reimbursement of Moderately Hypofractionated Postoperative Radiation Therapy for Breast Cancer: An International Consortium Report Clin Oncol (R Coll Radiol). 2021 May;33(5):322-330 2021
  • Milo MLH, Thorsen LBJ, Johnsen SP, Nielsen KM, Valentin JB, Alsner J, Offersen BV Risk of coronary artery disease after adjuvant radiotherapy in 29,662 early breast cancer patients: A population-based Danish Breast Cancer Group study Radiother Oncol. 2021 Apr;157:106-113 2021
  • Nielsen AWM, Kristensen MH, Offersen BV, Alsner J, Zachariae R, Nielsen HM Patient-reported outcomes in postmenopausal breast cancer survivors - comparisons with normative data Acta Oncol. 50: 78-86, 2021 2021
  • Nielsen AWM, Lundorff M, Nielsen HM, Alsner J, Vrou Offersen B, Kristensen MH, Zachariae R Symptom trajectories in breast cancer survivors: growth mixture analysis of patient-reported pain, fatigue, insomnia, breast and arm symptoms Acta Oncol. 2021 Dec;60(12):1659-1667 2021
  • Offersen BV, Poortmans P his house believes that all node positive breast cancer patients need post mastectomy radiation therapy Eur J Surg Oncol. 2021 Oct;47(10):2521-2524 2021
  • Rauff Søndergaard S, Ellekjær LB, Bechmann T, Offersen BV, Nielsen MH, Møller M, Berry LL, Zachariae R, Dahl Steffensen K Shared decision making with breast cancer patients: impact on patient engagement and fear of recurrence. Protocol for a Danish randomized trial in radiotherapy (DBCG RT SDM) Acta Oncol. 2021 Aug;60(8):1032-1037 2021
  • Stick LB, Lorenzen EL, Yates ES, Anandadas C, Andersen K, Aristei C, Byrne O, Hol S, Jensen I, Kirby AM, Kirova YM, Marrazzo L, Matías-Pérez A, Nielsen MMB, Nissen HD, Oliveros S, Verhoeven K, Vikström J, Offersen BV Selection criteria for early breast cancer patients in the DBCG proton trial - The randomised phase III trial strategy Clin Transl Radiat Oncol. 2021 Feb 4;27:126-131 2021
  • Thomsen MS, Berg M, Zimmermann S, Lutz CM, Makocki S, Jensen I, Hjelstuen MHB, Pensold S, Hasler MP, Jensen MB, Offersen BV Dose constraints for whole breast radiation therapy based on the quality assessment of treatment plans in the randomised Danish breast cancer group (DBCG) HYPO trial Clin Transl Radiat Oncol. 2021 Apr 6;28:118-123 2021
  • Tramm T, Christiansen P, Offersen BV, Madsen KB, Poortmans P, Kaidar-Person O Superficial margins in skin sparing and nipple sparing mastectomies for DCIS: A margin of potential concern Radiother Oncol. 2021 Aug;161:177-182 2021
  • Thomsen MS, Alsner J, Nielsen HM, Jakobsen EH, Nielsen MH, Møller M, Pedersen AN, Yates E, Berg M, Lorenzen E, Jensen I, Josipovic M, Overgaard J, Offersen BV; DBCG RT Committee Volume matters: Breast induration is associated with irradiated breast volume in the Danish Breast Cancer Group phase III randomized Partial Breast Irradiation trial Radiother Oncol. 2022 Dec;177:231-235 2022
  • Stick LB, Lægdsmand PMT, Bjerre HL, Høyer M, Jensen K, Jensen MF, Kronborg MB, Offersen BV, Kronborg CJS Spot-scanning proton therapy for targets with adjacent cardiac implantable electronic devices - Strategies for breast and head & neck cancer Phys Imaging Radiat Oncol. 2022 Feb 19;21:66-71 2022
  • Offersen BV, Overgaard M, Overgaard J. Breast cancer radiotherapy: Is it time to rethink the indication? Radiother Oncol. 2022 Dec;177:238-239 2022
  • Nankali S, Hansen R, Worm E, Yates ES, Thomsen MS, Offersen B, Poulsen PR Accuracy and potential improvements of surface-guided breast cancer radiotherapy in deep inspiration breath-hold with daily image-guidance Phys Med Biol. 2022 Sep 26;67(19) 2022
  • Meattini I, Becherini C, Boersma L, Kaidar-Person O, Marta GN, Montero A, Offersen BV, Aznar MC, Belka C, Brunt AM, Dicuonzo S, Franco P, Krause M, MacKenzie M, Marinko T, Marrazzo L, Ratosa I, Scholten A, Senkus E, Stobart H, Poortmans P, Coles CE. European Society for Radiotherapy and Oncology Advisory Committee in Radiation Oncology Practice consensus recommendations on patient selection and dose and fractionation for external beam radiotherapy in early breast cancer Lancet Oncol. 2022 Jan;23(1):e21-e31 2022
  • Johannessen AL, Alstrup M, Hjortdal VE, Offersen BV, Mohanakumar S. Lymphatic Function Decreases over Time in the Arms of Breast Cancer Patients following Treatment Plast Reconstr Surg Glob Open. 2022 Sep 16;10(9):e4507 2022
  • Fuglsang Jensen M, Stick LB, Høyer M, Kronborg CJS, Lorenzen EL, Mortensen HR, Nyström PW, Petersen SE, Randers P, Thai LMH, Yates ES, Offersen BV. Proton therapy for early breast cancer patients in the DBCG proton trial: planning, adaptation, and clinical experience from the first 43 patients Acta Oncol. 2022 Feb;61(2):223-230 2022