DK: Forsker i partikelterapi med protoner og tungere ioner. Et hovedemne er at finde ud af hvordan partiklernes vekslevirkninger under deres nedbremsning gennem patienten kan bruges bedst muligt, og derved give en bedre behandling. Dette kan bruges til nye behandlingsstrategier som "LET-painting" og såkaldt gitterterapi. Derudover forskes også i strålingsdosimetri, ikke kun for patientbehandling, men også for rumfart, idet fx. satelliter udsættes for ødelæggende partikelstråling i rummet.
UK: Research in particle therapy with protons and heavier ions. One of the main elements is to find out how particles change effect under their braking through the patient can be utilized best possible, and in this way give better treatment. This can be used for new treatment strategies such as "LET-painting" and so-called grating therapy. In addition, research in radiation dosimetry, not only for patient treatment but also for space travel as, for example, satellites encounter destructive corpuscular radiation in space.
Workgroups Publications- Proton Scanning and X-ray Beam Irradiation Induce Distinct Regulation of Inflammatory Cytokines in a Preclinical Mouse Model Int J Radiat Biol. 2020 Oct;96(10):1238-1244. 2020
- Comparison of Coding Transcriptomes in Fibroblasts Irradiated With Low and High LET Proton Beams and Cobalt-60 Photons. Int J Radiat Oncol Biol Phys. 2018 Dec 6 2018
- MONTE CARLO SIMULATIONS OF SPATIAL LET DISTRIBUTIONS IN CLINICAL PROTON BEAMS. Radiat Prot Dosimetry. 2018 Aug 1;180(1-4):296-299 2018
- Optimal reference genes for normalization of qPCR gene expression data from proton and photon irradiated dermal fibroblasts. Sci Rep. 2018 Aug 23;8(1):12688. 2018
- Validation of new 2D ripple filters in proton treatments of spherical geometries and non-small cell lung carcinoma cases. Phys Med Biol. 2018 Dec 14;63(24):245020 2018
- Ionization quenching in scintillators used for dosimetry of mixed particle fields Phys Med Biol. 2019 Apr 29;64(9):095018 2019
- THE ROLE OF PARTICLE SPECTRA IN MODELING THE RELATIVE BIOLOGICAL EFFECTIVENESS OF PROTON RADIOTHERAPY BEAMS Radiat Prot Dosimetry. 2019 May 1;183(1-2):251-254 2019
- Mapping initial and general recombination in scanning proton pencil beams. Phys Med Biol. 2020 Jun 5;65(11):115003 2020
- Dose- rather than fluence-averaged LET should be used as a single-parameter descriptor of proton beam quality for radiochromic film dosimetry Med Phys. 2020 Jun;47(5):2289-2299 2020
- A systematic review on the usage of averaged LET in radiation biology for particle therapy Radiother Oncol. 2021 Aug;161:211-221 2021
- Modeling RBE with other quantities than LET significantly improves prediction of in vitro cell survival for proton therapy Med Phys. 2022 Nov 2 2022