Kari Tanderup

Professor Kræftafdelingen/DCPT, Aarhus University Hospital karitand@rm.dk
Research interests

DK: Jeg har en stor interesse i stråleterapi i gynækologisk kræft. Jeg er formand for GEC ESTRO gyn arbejdsgruppen og er også i koordinator gruppen i EMBRACE studiet (embracestudy.dk). Jeg er især engageret i at udvikle en forbedret forståelse af udviklingen af toksicitet og sygdomsudfald og derudover engageret i forståelsen af relationen mellem klinisk udfald og patient/behandlings karakteristika. Samtidig er jeg interesseret i brachyterapi teknologi. Jeg koordinerer internationale indsatser for at facilitere og promovere in vivo dosimetri gennem netværksmøder, fælles forskningsaktiviteter og samarbejder med industri for at understøtte at forbedret teknologi kan blive tilgængelig for patienter. 

UK: I have a major interest in gynaecological cancer radiotherapy. I am chairing the GEC ESTRO gyn working group, and I am in the EMBRACE study coordinator group (www.embracestudy.dk). I am particularly engaged in developing improved understanding development of toxicity and disease outcome and to understand the relation between clinical outcome and patient/treatment characteristics. Furthermore, I am interested in brachytherapy technology. I am coordinating international efforts to facilitate and promote in vivo dosimetry through network meetings, joint research activities, and collaboration with industry to support that improved technology can become available for patients.

Workgroups Publications
  • Fokdal L, Tanderup K, Pötter R, Sturdza A, Kirchheiner K, Chargari C, Jürgenliemk-Schulz IM, Segedin B, Tan LT, Hoskin P, Mahantshetty U, Bruheim K, Rai B, Kirisits C, Lindegaard JC; EMBRACE collaborative group. Risk Factors for Ureteral Stricture After Radiochemotherapy Including Image Guided Adaptive Brachytherapy in Cervical Cancer: Results From the EMBRACE Studies Int J Radiat Oncol Biol Phys . 2019 Mar 15;103(4):887-894 2019
  • Sofia Spampinato, Lars U Fokdal, Richard Pötter, Christine Haie-Meder, Jacob C Lindegaard, Maximilian P Schmid, Alina Sturdza, Ina M Jürgenliemk-Schulz, Umesh Mahantshetty, Barbara Segedin, Kjersti Bruheim, Peter Hoskin, Bhavana Rai, Fleur Huang , Rachel Cooper, Elzbieta van der Steen-Banasik, Erik Van Limbergen, Marit Sundset, Henrike Westerveld, Remi A Nout, Nina B K Jensen, Christian Kirisits, Kathrin Kirchheiner, Kari Tanderup, EMBRACE Collaborative Group Importance of the ICRU bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: An EMBRACE analysis Radiother Oncol. 2021 May;158:300-308 2021
  • Nina B K Jensen, Richard Pötter, Sofia Spampinato, Lars U Fokdal, Cyrus Chargari , Jacob C Lindegaard , Maximilian P Schmid, Alina Sturdza, Ina M Jürgenliemk-Schulz, Umesh Mahantshetty, Barbara Segedin, Kjersti Bruheim, Peter Hoskin, Bhavana Rai, Ericka Wiebe, Rachel Cooper, Elzbieta Van der Steen-Banasik, Erik Van Limbergen, Marit Sundset, Bradley R Pieters, Remi A Nout, Christian Kirisits, Kathrin Kirchheiner, Kari Tanderup, EMBRACE Collaborative Group Dose-Volume Effects and Risk Factors for Late Diarrhea in Cervix Cancer Patients After Radiochemotherapy With Image Guided Adaptive Brachytherapy in the EMBRACE I Study Int J Radiat Oncol Biol Phys. 2021 Mar 1;109(3):688-700 2021
  • Erik B Jørgensen, Gustavo Kertzscher, Simon Buus, Lise Bentzen, Steffen B Hokland, Susanne Rylander, Kari Tanderup, Jacob G Johansen Accuracy of an in vivo dosimetry-based source tracking method for afterloading brachytherapy - A phantom study Med Phys. 2021 May;48(5):2614-2623 2021
  • Sandy Mohamed, Lars Fokdal, Marianne S Assenholt, Jesper Kallehauge, Jacob C Lindegaard, Kari Tanderup Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer J Appl Clin Med Phys. 2021 Oct;22(10):315-319 2021
  • Erik B Jørgensen, Jacob G Johansen, Joakim Overgaard, Dominique Piché-Meunier, Daline Tho, Haydee M L Rosales, Kari Tanderup, Luc Beaulieu, Gustavo Kertzscher, Sam Beddar A high-Z inorganic scintillator-based detector for time-resolved in vivo dosimetry during brachytherapy Med Phys. 2021 Nov;48(11):7382-7398 2021
  • Sofia Spampinato, Nina B K Jensen, Richard Pötter, Lars U Fokdal, Cyrus Chargari, Jacob C Lindegaard, Maximilian P Schmid, Alina Sturdza, Ina M Jürgenliemk-Schulz, Umesh Mahantshetty, Peter Hoskin, Barbara Segedin, Bhavana Rai, Kjersti Bruheim, Ericka Wiebe, Elzbieta Van der Steen-Banasik, Rachel Cooper, Erik Van Limbergen, Marit Sundset, Bradley R Pieters, Ludy C H W Lutgens, Li Tee Tan, Elena Villafranca, Stéphanie Smet, Noha Jastaniyah, Remi A Nout, Christian Kirisits, Supriya Chopra, Kathrin Kirchheiner, Kari Tanderup, Embrace Collaborative Group Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future Int J Radiat Oncol Biol Phys. 2022 Mar 1;112(3):681-693 2022
  • Erik B Jørgensen, Simon Buus, Lise Bentzen, Steffen B Hokland, Susanne Rylander, Gustavo Kertzscher, Sam Beddar, Kari Tanderup, Jacob G Johansen 3D dose reconstruction based on in vivo dosimetry for determining the dosimetric impact of geometric variations in high-dose-rate prostate brachytherapy Radiother Oncol. 2022 Jun;171:62-68 2022
  • Peter Georgi, Gustavo Kertzscher, Lars Nyvang, Jaroslav Šolc, Thorsten Schneider, Kari Tanderup, Jacob Graversen Johansen Toward 3D dose verification of an electronic brachytherapy source with a plastic scintillation detector Med Phys. 2022 May;49(5):3432-3443 2022
  • Spampinato S, Fokdal LU, Pötter R, Haie-Meder C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van der Steen-Banasik E, Van Limbergen E, Sundset M, Westerveld H, Nout RA, Jensen NBK, Kirisits C, Kirchheiner K, Tanderup K; EMBRACE Collaborative Group. Risk factors and dose-effects for bladder fistula, bleeding and cystitis after radiotherapy with imaged-guided adaptive brachytherapy for cervical cancer: an EMBRACE analysis Radiother Oncol . 2021 May;158:312-320 2021
  • Verhaegen, F., Fonseca, G.P., Johansen, J.G., Beaulieu, L., Beddar, S., Greer, P., Jornet, N., Kertzscher, G., McCurdy, B., Smith, R.L., Mijnheer, B., Olaciregui-Ruiz, I., Tanderup, K. Future directions of in vivo dosimetry for external beam radiotherapy and brachytherapy Physics and Imaging in Radiation Oncology, 2020, 16, pp. 18-19 2020
  • Fonseca, G.P., Johansen, J.G., Smith, R.L. Beaulieu, L., Beddar, S., Kertzscher, G.,Verhaegen, F., Tanderup, K In vivo dosimetry in brachytherapy: Requirements and future directions for research, development, and clinical practice Physics and Imaging in Radiation Oncology, 2020, 16, pp. 1-11 2020
  • Berger T, Godart J, Jagt T, Vittrup AS, Fokdal LU, Lindegaard JC, Jensen NBK, Zolnay A, Reijtenbagh D, Trnkova P, Tanderup K, Hoogeman M. Dosimetric Impact of Intrafraction Motion in Online-Adaptive Intensity Modulated Proton Therapy for Cervical Cancer Int J Radiat Oncol Biol Phys . 2021 Apr 1;109(5):1580-1587 2021
  • Chopra S, Mangaj A, Sharma A, Tan LT, Sturdza A, Jürgenliemk-Schulz I, Han K, Huang F, Schmid MP, Fokdal L, Chargari C, Diendorfer T, Tanderup K, Potter R, Nout RA Management of oligo-metastatic and oligo-recurrent cervical cancer: A pattern of care survey within the EMBRACE research network Radiother Oncol . 2020 Nov 2;155:151-159. 2020
  • Kirchheiner K, Smet S, Spampinato S, Jensen NBK, Vittrup AS, Fokdal L, Najjari-Jamal D, Westerveld HG, Lindegaard JC, Kirisits C, De Leeuw A, Schmid MP, Tan LT, Nout RA, Jürgenliemk-Schulz IM, Pötter R, Tanderup K Initiatives for education, training, and dissemination of morbidity assessment and reporting in a multiinstitutional international context: Insights from the EMBRACE studies on cervical cancer Brachytherapy . Nov-Dec 2020;19(6):837-849. 2020
  • van Houdt PJ, Kallehauge JF, Tanderup K, Nout R, Zaletelj M, Tadic T, van Kesteren ZJ, van den Berg CAT, Georg D, Côté JC, Levesque IR, Swamidas J, Malinen E, Telliskivi S, Brynolfsson P, Mahmood F, van der Heide UA Phantom-based quality assurance for multicenter quantitative MRI in locally advanced cervical cancer Radiother Oncol . 2020 Dec;153:114-121 2020
  • Tan LT, Tanderup K, Kirisits C, Mahantshetty U, Swamidas J, Jürgenliemk-Schulz I, Lindegaard J, de Leeuw A, Nesvacil N, Assenholt M, Berger D, Diendorfer T, Dimopoulos J, Duke S, Ecker S, Fokdal L, Hellebust T, Jensen N, Kirchheiner K, Nout R, Petric P, Schmid M, Seppenwoolde Y, Sturdza A, Van Limbergen E, Haie-Meder C, Pötter R Education and training for image-guided adaptive brachytherapy for cervix cancer-The (GEC)-ESTRO/EMBRACE perspective Brachytherapy . Nov-Dec 2020;19(6):827-836. 2020
  • J Knoth, R Pötter, I M Jürgenliemk-Schulz, C Haie-Meder, L Fokdal, A Sturdza, P Hoskin, U Mahantshetty, B Segedin, K Bruheim, E Wiebe, B Rai, R Cooper, E van der Steen-Banasik , E van Limbergen , B R Pieters, M Sundset, L T Tan, R A Nout, K Tanderup, C Kirisits, N Nesvacil, J C Lindegaard, M P Schmid Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study Gynecol Oncol . 2020 Oct;159(1):136-141. 2020
  • Vincent Grégoire, Matthias Guckenberger, Karin Haustermans, Jan J W Lagendijk, Cynthia Ménard, Richard Pötter, Ben J Slotman, Kari Tanderup, Daniela Thorwarth, Marcel van Herk, Daniel Zips Image guidance in radiation therapy for better cure of cancer Mol Oncol . 2020 Jul;14(7):1470-1491. 2020
  • Simon L Duke, Li-Tee Tan, Nina B K Jensen, Tamara Rumpold, Astrid A C De Leeuw, Christian Kirisits, Jacob C Lindegaard, Kari Tanderup, Richard C Pötter, Remi A Nout, Ina M Jürgenliemk-Schulz Implementing an online radiotherapy quality assurance programme with supporting continuous medical education - report from the EMBRACE-II evaluation of cervix cancer IMRT contouring Radiother Oncol . 2020 Jun;147:22-29. 2020
  • Johnna Perdrizet, David D'Souza, Julia Skliarenko, Michelle Ang, Lisa Barbera, Eric Gutierrez, Ananth Ravi, Kari Tanderup, Padraig Warde, Kelvin Chan, Wanrudee Isaranuwatchai, Michael Milosevic A Cost-Utility Analysis of Magnetic Resonance (MR) Guided Brachytherapy Versus Two-Dimensional and Computed Tomography (CT) Guided Brachytherapy for Locally Advanced Cervical Cancer Int J Radiat Oncol Biol Phys. 2020 Jul 1;107(3):512-521 2020
  • Lauren Bell, Lois Holloway, Kjersti Bruheim, Primož Petrič, Christian Kirisits, Kari Tanderup, Richard Pötter, Shalini Vinod, Karen Lim, Elise Pogson, Peter Metcalfe, Taran Paulsen Hellebust Dose planning variations related to delineation variations in MRI-guided brachytherapy for locally advanced cervical cancer Brachytherapy. Mar-Apr 2020;19(2):146-153 2020
  • Tanderup K, Nesvacil N, Kirchheiner K, Serban M, Spampinato S, Jensen NBK, Schmid M, Smet S, Westerveld H, Ecker S, Mahantshetty U, Swamidas J, Chopra S, Nout R, Tan LT, Fokdal L, Sturdza A, Jürgenliemk-Schulz I, de Leeuw A, Lindegaard JC, Kirisits C, Pötter R Evidence-Based Dose Planning Aims and Dose Prescription in Image-Guided Brachytherapy Combined With Radiochemotherapy in Locally Advanced Cervical Cancer Semin Radiat Oncol. 2020 Oct;30(4):311-327 2020
  • Vittrup AS, Tanderup K, Bentzen SM, Jensen NBK, Spampinato S, Fokdal LU, Lindegaard JC, Sturdza A, Schmid M, Segedin B, Jürgenliemk-Schulz IM, Bruheim K, Mahantshetty U, Haie-Meder C, Rai B, Cooper R, van der Steen-Banasik E, Sundset M, Huang F, Nout RA, Villafranca E, Van Limbergen E, Pieters BR, Tan LT, Lutgens LCHW, Hoskin P, Pötter R, Kirchheiner K; EMBRACE Collaborative Group. Persistence of Late Substantial Patient-Reported Symptoms (LAPERS) After Radiochemotherapy Including Image Guided Adaptive Brachytherapy for Locally Advanced Cervical Cancer: A Report From the EMBRACE Study Int J Radiat Oncol Biol Phys . 2021 Jan 1;109(1):161-173 2021
  • Johansen JG, Rylander S, Buus S, Bentzen L, Hokland SB, Søndergaard CS, With AKM, Kertzscher G, Tanderup K. Time-resolved in vivo dosimetry for source tracking in brachytherapy Brachytherapy. 2018 Jan - Feb; 17(1): 122-132 2018
  • Johansen JG, Kertzscher G, Jørgensen EB, Rylander S, Bentzen L, Hokland SB, Søndergaard CS, With AKM, Buus S, Tanderup K. Dwell time verification in brachytherapy based on time resolved in vivo dosimetry Phys Med. 2019 Apr;60:156-161. 2019
  • Linares Rosales HM, Johansen JG, Kertzscher G, Tanderup K, Beaulieu L, Beddar S 3D source tracking and error detection in HDR using two independent scintillator dosimetry systems Med Phys . 2021 May;48(5):2095-2107 2021
  • Kirchheiner K, Pötter R, Nout RA, Schwartz-Vittrup A, Holzner B, Bentzen SM, Tanderup K Late, persistent, substantial, treatment-related symptoms after radiotherapy (LAPERS): A new method for longitudinal analysis of late morbidity - applied in the EMBRACE study Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):300-309 2020
  • Spampinato S, Tanderup K, Marinovskij E, Axelsen S, Pedersen EM, Pötter R, Lindegaard JC, Fokdal L MRI-based contouring of functional sub-structures of the lower urinary tract in gynaecological radiotherapy Radiother Oncol. 2020 Apr;145:117-124 2020
  • Serban M, Kirisits C, de Leeuw A, Pötter R, Jürgenliemk-Schulz I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Oinam A, Bownes P, Oosterveld B, De Brabandere M, Koedooder K, Langeland Marthinsen AB, Whitney D, Lindegaard J, Tanderup K; EMBRACE Collaborative Group. Ring Versus Ovoids and Intracavitary Versus Intracavitary-Interstitial Applicators in Cervical Cancer Brachytherapy: Results From the EMBRACE I Study. Int J Radiat Oncol Biol Phys. 2020 Apr 1;106(5):1052-1062. 2020
  • Lindegaard JC, Petric P, Lindegaard AM, Tanderup K, Fokdal LU. Evaluation of a new prognostic tumor score in locally advanced cervical cancer integrating clinical examination and magnetic resonance imaging. nt J Radiat Oncol Biol Phys. 2020 Mar 15;106(4):754-763 2020
  • Swamidas J, Kirisits C, De Brabandere M, Hellebust TP, Siebert FA, Tanderup K. Image registration, contour propagation and dose accumulation of external beam and brachytherapy in gynecological radiotherapy. Radiother Oncol. 2020 Feb;143:1-11 2020
  • Vittrup AS, Tanderup K, Bentzen SM, Jensen NBK, Spampinato S, Fokdal LU, Lindegaard JC, Sturdza A, Schmid M, Segedin B, Jürgenliemk-Schulz IM, Bruheim K, Mahantshetty U, Haie-Meder C, Rai B, Cooper R, van der Steen-Banasik E, Sundset M, Huang F, Nout RA, Villafranca E, Van Limbergen E, Pieters BR, Tan LT, Lutgens LCHW, Hoskin P, Pötter R, Kirchheiner K; EMBRACE Collaborative Group. Persistence of late substantial patient-reported symptoms (LAPERS) after radiochemotherapy including image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study. Int J Radiat Oncol Biol Phys. 2020 Aug 24;S0360-3016(20)34139-0. 2020
  • Seppenwoolde Y, Assenholt MS, Georg D, Nout R, Tan LT, Rumpold T, de Leeuw A, Jürgenliemk-Schulz I, Kirisits C, Pötter R, Lindegaard JC, Tanderup K; EMBRACE Collaborative Group. Importance of training in external beam treatment planning for locally advanced cervix cancer: Report from the EMBRACE II dummy run. Radiother Oncol. 2019 Apr;133:149-155. 2019
  • Tan LT, Tanderup K, Hoskin P, Cooper, Pötter R Image-guided Adaptive Brachytherapy for Cervix Cancer - A Story of Successful Collaboration within the GEC-ESTRO GYN Network and the EMBRACE Studies. Clin Oncol (R Coll Radiol). 2018 Jul;30(7):397-399. 2018
  • Tanderup K, Kirisits C, Damato AL Treatment delivery verification in brachytherapy: Prospects of technology innovation. Brachytherapy. 2018 Jan - Feb;17(1):1-6. 2018
  • Berger T, Seppenwoolde Y, Pötter R, Assenholt MS, Lindegaard JC, Nout RA, de Leeuw A, Jürgenliemk-Schulz I, Tan LT, Georg D, Kirisits C, Dumas I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Fokdal L, Tanderup K; EMBRACE Collaborative Group. Importance of Technique, Target Selection, Contouring, Dose Prescription, and Dose-Planning in External Beam Radiation Therapy for Cervical Cancer: Evolution of Practice From EMBRACE-I to II. Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):885-894. 2019
  • Fokdal L, Pötter R, Kirchheiner K, Lindegaard JC, Jensen NBK, Kirisits C, Chargari C, Mahantshetty U, Jürgenliemk-Schulz IM, Segedin B, Hoskin P, Tanderup K. Physician assessed and patient reported urinary morbidity after radio-chemotherapy and image guided adaptive brachytherapy for locally advanced cervical cancer. Radiother Oncol. 127(3): 423-430 2018
  • Najjari Jamal D, Pötter R, Haie-Meder C, Lindegaard JC, Juergenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Wiebe E, Cooper R, Tanderup K, Kirchheiner K; EMBRACE collaborative group. Physician assessed and patient reported lower limb edema after definitive radio(chemo)therapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study. Radiother Oncol. 127(3), pp. 449-455 2018
  • Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, Tan LT, Haie-Meder C, Mahantshetty U, Segedin B, Hoskin P, Bruheim K, Rai B, Huang F, Van Limbergen E, Schmid M, Nesvacil N, Sturdza A, Fokdal L, Jensen NBK, Georg D, Assenholt M, Seppenwoolde Y, Nomden C, Fortin I, Chopra S, van der Heide U, Rumpold T, Lindegaard JC, Jürgenliemk-Schulz I; EMBRACE Collaborative Group. The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clinical and translational Radiation Oncology. 9: 48-60 2018
  • Smet S, Pötter R, Haie-Meder C, Lindegaard JC, Schulz-Juergenliemk I, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van Limbergen E, Tanderup K, Kirchheiner K; EMBRACE Collaborative Group. Fatigue, insomnia and hot flashes after definitive radiochemotherapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: An analysis from the EMBRACE study. Radiother Oncol. 127(3): pp. 440-448 2018
  • Vittrup AS, Kirchheiner K, Fokdal LU, Bentzen SM, Nout RA, Pötter R, Tanderup K Reporting of Late Morbidity After Radiation Therapy in Large Prospective Studies: A Descriptive Review of the Current Status. Int J Radiat Oncol Biol Phys. 2019 Aug 27. 2019
  • Serban M, Kirisits C, Pötter R, de Leeuw A, Nkiwane K, Dumas I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Oinam A, Bownes P, Oosterveld B, De Brabandere M, Koedooder K, Marthinsen ABL, Lindegaard J, Tanderup K; EMBRACE Collaborative Group Isodose surface volumes in cervix cancer brachytherapy: Change of practice from standard (Point A) to individualized image guided adaptive (EMBRACE I) brachytherapy. Radiother Oncol. 129 (3), pp. 567-574 2018
  • Spampinato S, Fokdal L, Marinovskij E, Axelsen S, Pedersen EM, Pötter R, Lindegaard JC, Tanderup K. Assessment of dose to functional sub-structures in the lower urinary tract in locally advanced cervical cancer radiotherapy. Phys Med. 2019 Mar;59:127-132. 2019
  • Jensen NBK, Pötter R, Kirchheiner K, Fokdal L, Lindegaard JC, Kirisits C, Mazeron R, Mahantshetty U, Jürgenliemk-Schulz IM, Segedin B, Hoskin P, Tanderup K; EMBRACE Collaborative Group. Bowel morbidity following radiochemotherapy and image-guided adaptive brachytherapy for cervical cancer: Physician- and patient reported outcome from the EMBRACE study. Radiother Oncol. 2018 Jun; 127(3): 431-439 2018